Manufactured by:ProteoGenix
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MousePAD2 Protein-arginine deiminase type-2 Mouse Recombinant Protein

MousePAD2 Protein-arginine deiminase type-2 Mouse Recombinant Protein from ProteoGenix; catalogue PX-P3022; research use only.

SKU:
ABM146010-1
Manufacturer SKU
PX-P3022
Product type
Recombinant Proteins
ApplicationsELISA, WB
Expression systemEukaryotic expression
Purity95%

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

General Information about Mouse PAD2 (PADI2)

Mouse PAD2 (PADI2) is a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions.

PADI2 has peptidylarginine deiminase activity against synthetic substrates. PAD2 is mainly expressed in the central nervous system, skeletal muscle, spinal cord, cerebrum, cerebellum, and submaxillary gland. Protein arginine deiminase type-2 plays a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis.

Eukaryote expression systems and more specifically Insect cells are used at ProteoGenix to produce mouse PAD2 recombinant protein with appropriate post translational modifications.

ProteoGenix catalogue number PX-P3022. For research use only.

Host: Insect; Expression system: Eukaryotic expression; Purity: 95%; Molecular weight: 79.36 kDa; Tag: Yes; Fragment: Full-length; Buffer: 50mM Tris-Cl pH 8.0, 150mM NaCl; Applications: ELISA, WB.

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Download the manufacturer safety data sheet (MSDS/SDS)

Key facts & specifications
Also known as
PAD-H19, PAD2, PDI2, Peptidylarginine deiminase II
Host species
Insect
Source organism
House Mouse
Tag
Yes
Molecular weight
79.36 kDa
Form / buffer
Lyophilized
Activity
Calcium-dependent critrullination activity of the recombinant PAD2 was confirmed with Fibrinogen as substrate (detection of critrullinated fibrinogen by ELISA).
Sequence fragment
Full-length
Sequence
MQPPIRENMLRERTVRLQYGSRVEAVYVLGTQLWTDVYSAAPAGAKTFSLKHSEGVKVEVVRDGEAEEVVTNGKQRWALSPSSTLRLSMAQASTEASSDKVTVNYYEEEGSAPIDQAGLFLTAIEISLDVDADRDGEVEKNNPKKASWTWGPEGQGAILLVNCDRDTPWLPKEDCSDEKVYSKQDLQDMSQMILRTKGPDRLPAGYEIVLYISMSDSDKVGVFYVENPFFGQRYIHILGRQKLYHVVKYTGGSAELLFFVEGLCFPDESFSGLVSIHVSLLEYMAEGIPLTPIFTDTVMFRIAPWIMTPNILPPVSVFVCCMKDNYLFLKEVKNLVEKTNCELKVCFQYMNRGDRWIQDEIEFGYIEAPHKGFPVVLDSPRDGNLKDFPIKQLLGPDFGYVTREPLFETVTSLDSFGNLEVSPPVTVNGKEYPLGRILIGSSFPLSGGRRMTKVVRDFLQAQQVQAPVELYSDWLTVGHVDEFMTFIPIPGKKEFRLLMASTSACYQLFREKQKAGHGEAVMFKGLGGMSSKRITINKILSNESLTQENQYFQRCLDWNRDILKRELALTEKDIIDLPALFKMDENHQARAFFPNMVNMIVLDKDLGIPKPFGPQVEEECCLETHVRGLLEPLGLACTFIDDISAYHKFLGEVHCGTNVRRKPFTFKWWHMVP
Technical note
For research use only
Identifiers & database references
Manufacturer SKU
PX-P3022
UniProt accession
Q08642
NCBI accession
NP_032838.2
Storage, stability & shipping
Storage conditions
4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
Shipped at
Dry Ice
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
£245.00£196.00