Epacmarstobart Biosimilar – Anti-BIT mAb – Research Grade from ProteoGenix; catalogue PX-TA2063; research use only.
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Epacmarstobart Biosimilar – Anti-BIT mAb is a research grade antibody that has been developed as a biosimilar to the original anti-BIT monoclonal antibody (mAb). This biosimilar has been designed to have a similar structure, activity and application as the original antibody, while also providing researchers with a more cost-effective option for their studies.
The structure of Epacmarstobart Biosimilar – Anti-BIT mAb is very similar to that of the original anti-BIT mAb. It is a monoclonal antibody, meaning it is produced by a single clone of cells and is therefore highly specific in its binding to its target. The antibody consists of two heavy chains and two light chains, which are connected by disulfide bonds. The variable regions of the antibody, responsible for binding to the target, are located at the tips of the heavy and light chains.
The amino acid sequence of Epacmarstobart Biosimilar – Anti-BIT mAb has been carefully engineered to be as close as possible to the original antibody, while also ensuring high specificity and binding affinity for the target. This ensures that the biosimilar will have a similar activity and efficacy as the original antibody.
The main activity of Epacmarstobart Biosimilar – Anti-BIT mAb is its ability to bind to the therapeutic target, BIT (B-cell inhibitory receptor). This receptor is found on the surface of B-cells, a type of white blood cell involved in the immune response. By binding to BIT, the antibody blocks its activity and prevents the activation and proliferation of B-cells.
This activity is important in a variety of diseases and conditions where B-cell overactivity is a contributing factor. For example, in autoimmune diseases such as rheumatoid arthritis and lupus, B-cells play a major role in the immune response, leading to tissue damage. By targeting and inhibiting BIT, Epacmarstobart Biosimilar – Anti-BIT mAb can help to reduce the activity of B-cells and alleviate symptoms of these diseases.
In addition, Epacmarstobart Biosimilar – Anti-BIT mAb has also shown promising results in the treatment of B-cell malignancies, such as lymphoma and leukemia. By targeting and inhibiting BIT, the antibody can help to slow the growth and spread of these cancer cells.
Epacmarstobart Biosimilar – Anti-BIT mAb has a wide range of applications in both research and clinical settings. In research, the biosimilar can be used to study the role of B-cells and BIT in various diseases and conditions. Its high specificity and binding affinity make it a valuable tool for studying the mechanisms of action of these cells and identifying potential therapeutic targets.
In the clinic, Epacmarstobart Biosimilar – Anti-BIT mAb has the potential to be used as a treatment for a variety of diseases and conditions. Its ability to target and inhibit BIT makes it a promising therapy for autoimmune diseases and B-cell malignancies. In addition, the biosimilar may also have applications in transplantation, as B-cells play a role in the rejection of transplanted organs.
Overall, Epacmarstobart Biosimilar – Anti-BIT mAb offers a cost-effective and highly specific alternative to the original anti-BIT mAb. Its similar structure, activity and application make it a valuable tool for researchers and a promising therapeutic option for a range of diseases and conditions.
In summary, Epacmarstobart Biosimilar – Anti-BIT mAb is a research grade antibody that has been developed as a biosimilar to the original anti-BIT mAb. Its structure is similar to the original antibody, with carefully engineered amino acid sequences to ensure high specificity and binding affinity for the target. The main activity of the biosimilar is its
ProteoGenix catalogue number PX-TA2063. For research use only.
Target: Epacmarstobart Biosimilar – Anti-BIT mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: XtenCHO; Purity: >90% by SDS-PAGE.; Buffer: 0.01M PBS, pH 7.4.; Applications: ELISA, WB.
Available configurations: 100ug, 1mg.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Target | WB | IHC-P | IHC-Fr | IF/ICC | Flow Cyt | IP | ChIP | ELISA |
|---|---|---|---|---|---|---|---|---|
| Epacmarstobart Biosimilar – Anti-BIT mAb – Research Grade |
This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
