Manufactured by:ProteoGenix
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Enibarcimab Biosimilar – Anti-ADM mAb – Research Grade

Enibarcimab Biosimilar – Anti-ADM mAb – Research Grade from ProteoGenix; catalogue PX-TA1664; research use only.

SKU:
ABM134384-1
Manufacturer SKU
PX-TA1664
Product type
Primary Antibodies
TargetEnibarcimab Biosimilar – Anti-ADM mAb – Research Grade
ApplicationsELISA, WB
Expression systemXtenCHO
Purity>85%

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Introduction to Enibarcimab Biosimilar – Anti-ADM mAb – Research Grade

Enibarcimab Biosimilar, also known as Anti-ADM mAb, is a monoclonal antibody that specifically targets adrenomedullin (ADM), a hormone involved in various physiological processes. This biosimilar is a promising therapeutic option for various diseases and is currently in the research stage. In this article, we will explore the structure, activity, and potential applications of Enibarcimab Biosimilar in detail.

Structure of Enibarcimab Biosimilar

Enibarcimab Biosimilar is a monoclonal antibody, which means it is a laboratory-produced protein that mimics the natural antibodies produced by the immune system. The structure of this biosimilar is similar to that of the original Enibarcimab, with minor differences due to the manufacturing process. It is a Y-shaped protein made up of two identical heavy chains and two identical light chains. The heavy chains are further divided into constant and variable regions, with the variable regions responsible for binding to the target, ADM.

Activity of Enibarcimab Biosimilar

Enibarcimab Biosimilar works by binding to ADM and blocking its activity. ADM is a hormone that plays a crucial role in regulating blood pressure, inflammation, and tissue repair. However, in certain diseases, such as sepsis and acute respiratory distress syndrome (ARDS), excessive levels of ADM can lead to harmful effects. By binding to ADM, Enibarcimab Biosimilar can reduce its levels and prevent its harmful effects, making it a potential therapeutic option for these diseases.

Title: Potential Applications of Enibarcimab Biosimilar

Enibarcimab Biosimilar has shown promising results in preclinical studies for the treatment of sepsis and ARDS. Sepsis is a life-threatening condition caused by an overwhelming immune response to an infection, and ARDS is a severe lung condition that can occur as a result of sepsis or other diseases. By targeting ADM, Enibarcimab Biosimilar has the potential to reduce inflammation and improve outcomes in these conditions.

Apart from sepsis and ARDS, Enibarcimab Biosimilar may also have potential applications in other diseases. For example, ADM has been implicated in the development of certain types of cancer, and Enibarcimab Biosimilar could potentially be used as a targeted therapy in these cases. Additionally, ADM has been linked to cardiovascular diseases, and Enibarcimab Biosimilar may have a role in reducing the risk of these conditions.

Advantages of Enibarcimab Biosimilar

Enibarcimab Biosimilar offers several advantages over the original Enibarcimab. As a biosimilar, it is expected to have a similar safety and efficacy profile as the original drug, but at a lower cost. This makes it a more accessible option for patients who may not be able to afford the original drug. Additionally, the manufacturing process of biosimilars is more streamlined, making them more readily available for patients in need.

Conclusion

In conclusion, Enibarcimab Biosimilar, also known as Anti-ADM mAb, is a promising therapeutic option for various diseases. Its structure, activity, and potential applications make it a valuable addition to the field of targeted therapies. With ongoing research and clinical trials, Enibarcimab Biosimilar has the potential to improve outcomes for patients with sepsis, ARDS, and other diseases associated with high levels of ADM.

ProteoGenix catalogue number PX-TA1664. For research use only.

Target: Enibarcimab Biosimilar – Anti-ADM mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: XtenCHO; Purity: >85%; Buffer: PBS buffer PH7.5; Applications: ELISA, WB.

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Key facts & specifications
Also known as
Enibarcimab,ENIBARCIMAB, HAM8101, HAM-8101, IMMUNOGLOBULIN G1, ANTI-(HUMAN ADRENOMEDULLIN) (HUMAN-MUS MUSCULUS MONOCLONAL HAM8101 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL HAM8101 .KAPPA.-CHAIN, DIMER, IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS ADM (ADRENOMEDULLIN)), MONOCLONAL ANTIBODY,ADM,anti-ADM
Clonality
Monoclonal
Isotype
IgG1,Kappa
Source organism
CAS 2305638-98-4
Sequence
MKLVSVALMYLGSLAFLGADTARLDVASEFRKKWNKWALSRGKRELRMSSSYPTGLADVKAGPAQTLIRPQDMKGASRSPEDSSPDAARIRVKRYRQSMNNFQGLRSFGCRFGTCTVQKLAHQIYQFTDKDKDNVAPRSKISPQGYGRRRRRSLPEAGPGRTLVSSKPQAHGAPAPPSGSAPHFL
Technical note
For research use only. Not suitable for clinical or therapeutic use.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation

Evidence status by application and model.

TargetWBIHC-PIHC-FrIF/ICCFlow CytIPChIPELISA
Enibarcimab Biosimilar – Anti-ADM mAb – Research Grade
Identifiers & database references
Manufacturer SKU
PX-TA1664
UniProt accession
P35318
Storage, stability & shipping
Storage conditions
store at -80°C
Shipped at
Blue ice (+4°C)
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
£139.00£111.20