Manufactured by:ProteoGenix
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Dazukibart Biosimilar – Anti-IFNB mAb – Research Grade

Dazukibart Biosimilar – Anti-IFNB mAb – Research Grade from ProteoGenix; catalogue PX-TA1941; research use only.

SKU:
ABM134120-1
Manufacturer SKU
PX-TA1941
Product type
Primary Antibodies
TargetDazukibart Biosimilar – Anti-IFNB mAb – Research Grade
ApplicationsELISA, WB
Expression systemXtenCHO

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Introduction

Dazukibart Biosimilar – Anti-IFNB mAb – Research Grade is a monoclonal antibody (mAb) that specifically targets and binds to the interferon beta (IFNB) protein. This biosimilar is a highly effective and safe therapeutic option for various autoimmune diseases, including multiple sclerosis and rheumatoid arthritis.

Structure of Dazukibart Biosimilar

Dazukibart Biosimilar is a recombinant, humanized IgG1 monoclonal antibody, with a molecular weight of approximately 150 kDa. It is produced using recombinant DNA technology, where the genes encoding for the heavy and light chains of the antibody are inserted into a host cell, such as Chinese hamster ovary (CHO) cells. The resulting antibody is highly purified and has a consistent structure, making it a reliable treatment option.

Mechanism of Action

Dazukibart Biosimilar works by binding to the IFNB protein, which is a cytokine involved in regulating the immune response. By binding to IFNB, Dazukibart Biosimilar blocks its activity and prevents it from signaling immune cells to attack healthy tissues. This reduces inflammation and tissue damage, providing relief to patients with autoimmune diseases.

Therapeutic Applications

Dazukibart Biosimilar is primarily used for the treatment of multiple sclerosis (MS), a chronic autoimmune disease that affects the central nervous system. It is also being studied for its potential use in other autoimmune diseases, such as rheumatoid arthritis and psoriasis.

In clinical trials, Dazukibart Biosimilar has shown significant efficacy in reducing the frequency and severity of MS relapses. It has also been found to delay disease progression and improve overall quality of life in MS patients. This makes it a valuable therapeutic option for those living with this debilitating disease.

Research Grade

Dazukibart Biosimilar is available in a research grade form, which is specifically designed for use in laboratory studies and preclinical research. This grade of the antibody is highly purified and has a consistent structure, making it ideal for use in various research applications.

Researchers can use Dazukibart Biosimilar to study the mechanisms of action of IFNB and its role in autoimmune diseases. It can also be used to test the efficacy and safety of new treatment approaches for MS and other autoimmune disorders.

Conclusion

In summary, Dazukibart Biosimilar – Anti-IFNB mAb – Research Grade is a highly effective and safe therapeutic option for autoimmune diseases, particularly multiple sclerosis. Its specific targeting of the IFNB protein and consistent structure make it a valuable tool for research and potential treatment of other autoimmune disorders. With ongoing research and development, Dazukibart Biosimilar has the potential to improve the lives of many patients living with these debilitating conditions.

ProteoGenix catalogue number PX-TA1941. For research use only.

Target: Dazukibart Biosimilar – Anti-IFNB mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: XtenCHO; Buffer: 0.01M PBS, pH 7.4; Applications: ELISA, WB.

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Key facts & specifications
Also known as
anti-IFNB, IFN-beta, Interferon beta, IFNB1, Fibroblast interferon, IFB
Clonality
Monoclonal
Isotype
IgG1-kappa
Source organism
CAS: 2639474-65-8
Sequence
MTNKCLLQIALLLCFSTTALSMSYNLLGFLQRSSNFQCQKLLWQLNGRLEYCLKDRMNFDIPEEIKQLQQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQINHLKTVLEEKLEKEDFTRGKLMSSLHLKRYYGRILHYLKAKEYSHCAWTIVRVEILRNFYFINRLTGYLRN
Technical note
For research use only. Not suitable for clinical or therapeutic use.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation

Evidence status by application and model.

TargetWBIHC-PIHC-FrIF/ICCFlow CytIPChIPELISA
Dazukibart Biosimilar – Anti-IFNB mAb – Research Grade
Identifiers & database references
Manufacturer SKU
PX-TA1941
UniProt accession
P01574
Storage, stability & shipping
Storage conditions
store at -80°C
Shipped at
Blue ice (+4°C)
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
£155.00£124.00