Manufactured by:ProteoGenix
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Anti-Tupaia chinensis CD152/CTLA4 Polyclonal Antibody

Anti-Tupaia chinensis CD152/CTLA4 Polyclonal Antibody from ProteoGenix; catalogue ARO-A22183; research use only.

SKU:
ABM121586-1
Manufacturer SKU
ARO-A22183
Product type
Primary Antibodies
Targetcytotoxic T-lymphocyte protein 4 isoform X1; CTLA4
ApplicationsIHC, ELISA

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Anti-Tupaia chinensis CD152/CTLA4 Polyclonal Antibody

The Anti-Tupaia chinensis CD152/CTLA4 Polyclonal Antibody is a highly specific and reliable tool for studying the immune response in Tupaia chinensis, a small mammal commonly used in biomedical research. This antibody targets the CD152/CTLA4 protein, which plays a crucial role in regulating T cell activation and immune tolerance.

Biological Function:

CD152/CTLA4 is a cell surface protein expressed on T cells that acts as a negative regulator of the immune response. It competes with the co-stimulatory molecule CD28 for binding to the ligands CD80 and CD86 on antigen-presenting cells, resulting in the suppression of T cell activation and proliferation. This process helps to maintain immune homeostasis and prevent excessive immune responses that can lead to autoimmune diseases.

Main Applications:

The Anti-Tupaia chinensis CD152/CTLA4 Polyclonal Antibody is an essential tool for studying the function of CD152/CTLA4 in Tupaia chinensis. It can be used in various applications, including flow cytometry, immunohistochemistry, and western blotting. This antibody is also suitable for in vivo studies, such as blocking experiments to investigate the role of CD152/CTLA4 in immune response regulation.

Experimental Use Cases:

One of the main experimental use cases for this antibody is in the study of immune tolerance and autoimmune diseases. By blocking the CD152/CTLA4 protein, researchers can observe the effects on T cell activation and immune response, providing valuable insights into the underlying mechanisms of these conditions. Additionally, this antibody can be used to investigate the potential therapeutic effects of targeting CD152/CTLA4 in the treatment of autoimmune diseases.

This antibody is highly specific and reliable for studying the immune response in Tupaia chinensis. It targets the CD152/CTLA4 protein, which plays a crucial role in regulating T cell activation and immune tolerance. The Anti-Tupaia chinensis CD152/CTLA4 Polyclonal Antibody is an essential tool for flow cytometry, immunohistochemistry, and western blotting experiments, as well as in vivo studies. It is particularly useful for investigating immune tolerance and potential therapeutic approaches for autoimmune diseases.

In summary, the Anti-Tupaia chinensis CD152/CTLA4 Polyclonal Antibody is a valuable tool for understanding the role of CD152/CTLA4 in the immune response of Tupaia chinensis. Its high specificity and reliability make it an ideal choice for various experimental applications, providing valuable insights into immune tolerance and potential treatment options for autoimmune diseases. Order now to advance your research in this field.

ProteoGenix catalogue number ARO-A22183. For research use only.

Target: cytotoxic T-lymphocyte protein 4 isoform X1; CTLA4; Clonality: Polyclonal Antibody; Applications: IHC, ELISA.

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Key facts & specifications
Clonality
Polyclonal
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation

Evidence status by application and model.

TargetWBIHC-PIHC-FrIF/ICCFlow CytIPChIPELISAIHC
cytotoxic T-lymphocyte protein 4 isoform X1; CTLA4
Identifiers & database references
Manufacturer SKU
ARO-A22183
Storage, stability & shipping
Storage conditions
4°C for short term (1 week), store at -20°C to -80°C for long term(1 year); Avoid repeated freeze-thaw cycles
Shipped at
Blue ice (+4°C)
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
£189.00£151.20