Manufactured by:ProteoGenix
Save 20%RUO

Anti-TDO2 Polyclonal Antibody

Anti-TDO2 Polyclonal Antibody from ProteoGenix; catalogue ARO-A22424; research use only.

SKU:
ABM121449-1
Manufacturer SKU
ARO-A22424
Product type
Primary Antibodies
TargetTryptophan 23-dioxygenase, TDO, EC:1.13.11.11, Tryptamin 23-dioxygenase, Tryptophan oxygenase, TO, TRPO, Tryptophan pyrrolase, Tryptophanase, TDO2, TDO
ApplicationsIHC, ELISA

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

Anti-TDO2 Polyclonal Antibody: A Powerful Tool for Studying Tryptophan Metabolism in Biotech Research

Introduction:

Tryptophan is an essential amino acid that plays a crucial role in various biological processes, including protein synthesis and neurotransmitter production. However, excessive levels of tryptophan can lead to the production of toxic metabolites, which can have detrimental effects on the body. This is where the Anti-TDO2 Polyclonal Antibody comes in – a highly specific and sensitive tool for studying tryptophan metabolism in biotech research.

Biological Function:

The Anti-TDO2 Polyclonal Antibody targets the enzyme Tryptophan 2,3-dioxygenase 2 (TDO2), which is responsible for the conversion of tryptophan to kynurenine. This antibody binds to TDO2 with high affinity, inhibiting its activity and allowing for the accurate measurement of tryptophan levels in biological samples.

Main Applications:

This antibody is a valuable tool for researchers studying tryptophan metabolism and its effects on various diseases, including cancer, autoimmune disorders, and neurological disorders. It can also be used to investigate the role of TDO2 in immune tolerance and inflammation.

Experimental Use Cases:

1. Measurement of Tryptophan Levels: The Anti-TDO2 Polyclonal Antibody can be used in ELISA or Western blot assays to measure tryptophan levels in biological samples, providing valuable insights into the regulation of tryptophan metabolism in different conditions.

2. Inhibition of TDO2 Activity: By binding to TDO2, this antibody can inhibit its activity and prevent the production of toxic metabolites. This is particularly useful in cancer research, where TDO2 is overexpressed and contributes to tumor growth.

3. Identification of TDO2 Interacting Proteins: The Anti-TDO2 Polyclonal Antibody can be used in co-immunoprecipitation experiments to identify proteins that interact with TDO2, providing a better understanding of its role in various biological processes.

Conclusion:
The Anti-TDO2 Polyclonal Antibody is a powerful tool for studying tryptophan metabolism in biotech research. Its high specificity and sensitivity make it an ideal choice for accurately measuring tryptophan levels and inhibiting TDO2 activity. With its various applications and experimental use cases, this antibody is a must-have for any researcher looking to gain a deeper understanding of tryptophan metabolism and its implications in disease. Order now and take your biotech research to the next level.

ProteoGenix catalogue number ARO-A22424. For research use only.

Target: Tryptophan 23-dioxygenase, TDO, EC:1.13.11.11, Tryptamin 23-dioxygenase, Tryptophan oxygenase, TO, TRPO, Tryptophan pyrrolase, Tryptophanase, TDO2, TDO; Clonality: Polyclonal Antibody; Applications: IHC, ELISA.

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Key facts & specifications
Clonality
Polyclonal
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation

Evidence status by application and model.

TargetWBIHC-PIHC-FrIF/ICCFlow CytIPChIPELISAIHC
Tryptophan 23-dioxygenase, TDO, EC
Identifiers & database references
Manufacturer SKU
ARO-A22424
Storage, stability & shipping
Storage conditions
4°C for short term (1 week), store at -20°C to -80°C for long term(1 year); Avoid repeated freeze-thaw cycles
Shipped at
Blue ice (+4°C)
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
£205.00£164.00