Manufactured by:ProteoGenix
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Anti-SIV Nef Polyclonal Antibody

Anti-SIV Nef Polyclonal Antibody from ProteoGenix; catalogue ARO-A22443; research use only.

SKU:
ABM121438-1
Manufacturer SKU
ARO-A22443
Product type
Primary Antibodies
Targetnef protein, nef
ApplicationsIHC, ELISA

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Anti-SIV Nef Polyclonal Antibody: A Powerful Tool for Studying Simian Immunodeficiency Virus

Introduction:

The Anti-SIV Nef Polyclonal Antibody is a highly specific and sensitive tool for studying the Simian Immunodeficiency Virus (SIV). This antibody is produced by immunizing rabbits with a synthetic peptide derived from the Nef protein of SIV. It has been extensively validated for use in various research applications and has shown excellent results in numerous experiments.

Biological Function:

The Nef protein is a key regulator of SIV replication and pathogenesis. It plays a crucial role in viral infectivity, immune evasion, and disease progression. The Anti-SIV Nef Polyclonal Antibody specifically targets this protein and can effectively neutralize its function, making it an essential tool for studying the mechanisms of SIV infection.

Main Applications:

This antibody has a wide range of applications in SIV research, including:

1. Detection of SIV-infected cells: The Anti-SIV Nef Polyclonal Antibody can be used for immunofluorescence and immunohistochemistry to detect SIV-infected cells in tissue samples. Its high specificity ensures accurate and reliable results.

2. Western blotting: This antibody has been successfully used in western blotting to detect the Nef protein in SIV-infected cell lysates. It can also be used for quantification of viral load in samples.

3. Flow cytometry: The Anti-SIV Nef Polyclonal Antibody is suitable for flow cytometry analysis of SIV-infected cells. It can be used to identify and isolate specific cell populations for further study.

Experimental Use Cases:

The Anti-SIV Nef Polyclonal Antibody has been used in various experimental settings with excellent results. For example:

1. Inhibition of viral replication: In a recent study, this antibody was used to block the function of Nef protein in SIV-infected cells, resulting in a significant reduction in viral replication.

2. Study of viral pathogenesis: By targeting the Nef protein, this antibody has been used to investigate the role of SIV in immune suppression and disease progression.

3. Vaccine development: The Anti-SIV Nef Polyclonal Antibody has been used in pre-clinical studies to evaluate the efficacy of potential SIV vaccines.

Conclusion:
In summary, the Anti-SIV Nef Polyclonal Antibody is a highly specific and sensitive tool for studying the Simian Immunodeficiency Virus. Its ability to target the Nef protein makes it an essential reagent for various research applications. With its proven effectiveness and versatility, this antibody is a valuable addition to any SIV research toolkit.

Keywords: Anti-SIV Nef Polyclonal Antibody, Simian Immunodeficiency Virus, Nef protein, immunofluorescence, immunohistochemistry, western blotting, flow cytometry, viral replication, viral pathogenesis, vaccine development.

ProteoGenix catalogue number ARO-A22443. For research use only.

Target: nef protein, nef; Clonality: Polyclonal Antibody; Applications: IHC, ELISA.

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Key facts & specifications
Clonality
Polyclonal
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation

Evidence status by application and model.

TargetWBIHC-PIHC-FrIF/ICCFlow CytIPChIPELISAIHC
nef protein, nef
Identifiers & database references
Manufacturer SKU
ARO-A22443
Storage, stability & shipping
Storage conditions
4°C for short term (1 week), store at -20°C to -80°C for long term(1 year); Avoid repeated freeze-thaw cycles
Shipped at
Blue ice (+4°C)
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
£205.00£164.00