Manufactured by:ProteoGenix
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Anti-PTGIS Polyclonal Antibody

Anti-PTGIS Polyclonal Antibody from ProteoGenix; catalogue ARO-A22141; research use only.

SKU:
ABM121627-1
Manufacturer SKU
ARO-A22141
Product type
Primary Antibodies
TargetProstacyclin synthase; 5.3.99.4; Hydroperoxy icosatetraenoate dehydratase; 4.2.1.152; Prostaglandin I2 synthase; Ptgis; Cyp8
ApplicationsIHC, ELISA

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Anti-PTGIS Polyclonal Antibody: A Powerful Tool for Studying Prostaglandin Synthesis

Introduction:

Prostaglandins are lipid molecules that play a crucial role in various physiological processes, including inflammation, pain, and blood clotting. Prostaglandin synthase (PTGIS) is an enzyme that catalyzes the conversion of prostaglandin H2 into prostacyclin, a potent anti-inflammatory and vasodilatory agent. The dysregulation of PTGIS has been linked to numerous diseases, making it an important target for research and drug development. The Anti-PTGIS Polyclonal Antibody is a reliable and specific tool for studying PTGIS and its role in various biological processes.

Biological Function:

The Anti-PTGIS Polyclonal Antibody is designed to specifically recognize and bind to PTGIS, allowing for the detection and quantification of the enzyme in various biological samples. This antibody is raised against a recombinant protein corresponding to the full-length human PTGIS, ensuring high specificity and sensitivity. It can be used for both immunohistochemistry and western blotting applications.

Main Applications:

The Anti-PTGIS Polyclonal Antibody is a valuable tool for both basic research and drug discovery. It can be used to study the expression and localization of PTGIS in different tissues and cell types. Additionally, this antibody can be used to investigate the regulation of PTGIS in various disease models, such as inflammation, cardiovascular diseases, and cancer. Its high specificity and sensitivity make it an ideal choice for screening potential PTGIS inhibitors and evaluating their efficacy.

Experimental Use Cases:

1. Immunohistochemistry: The Anti-PTGIS Polyclonal Antibody can be used to study the expression and localization of PTGIS in tissue sections. For example, it can be used to determine the distribution of PTGIS in different regions of the brain or in tumor tissues.

2. Western Blotting: This antibody can be used to detect and quantify PTGIS protein levels in cell lysates or tissue homogenates. It can be used to compare the expression of PTGIS in different samples or to monitor changes in PTGIS levels under different experimental conditions.

3. Drug Discovery: The Anti-PTGIS Polyclonal Antibody can be used to screen potential PTGIS inhibitors and evaluate their potency. It can also be used to study the mechanism of action of these inhibitors and their effects on PTGIS activity.

In conclusion, the Anti-PTGIS Polyclonal Antibody is a reliable and specific tool for studying PTGIS and its role in various biological processes. Its high specificity and sensitivity make it an ideal choice for both basic research and drug discovery. Order now and advance your research on prostaglandin synthesis.

ProteoGenix catalogue number ARO-A22141. For research use only.

Target: Prostacyclin synthase; 5.3.99.4; Hydroperoxy icosatetraenoate dehydratase; 4.2.1.152; Prostaglandin I2 synthase; Ptgis; Cyp8; Clonality: Polyclonal Antibody; Applications: IHC, ELISA.

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Key facts & specifications
Clonality
Polyclonal
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation

Evidence status by application and model.

TargetWBIHC-PIHC-FrIF/ICCFlow CytIPChIPELISAIHC
Prostacyclin synthase; 5.3.99.4; Hydroperoxy icosatetraenoate dehydratase; 4.2.1.152; Prostaglandin I2 synthase; Ptgis; Cyp8
Identifiers & database references
Manufacturer SKU
ARO-A22141
Storage, stability & shipping
Storage conditions
4°C for short term (1 week), store at -20°C to -80°C for long term(1 year); Avoid repeated freeze-thaw cycles
Shipped at
Blue ice (+4°C)
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
£189.00£151.20