Anti-Mouse MMP3 Antibody (CH01) from ProteoGenix; catalogue ARO-A15080; research use only.
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Anti-Mouse MMP3 Antibody (CH01) is a highly specific and potent monoclonal antibody that targets the matrix metalloproteinase 3 (MMP3) protein in mice. MMP3 is a member of the matrix metalloproteinase family, which are enzymes involved in the breakdown of extracellular matrix proteins. MMP3 has been implicated in various physiological and pathological processes, making it a promising therapeutic target for a range of diseases. In this article, we will provide a detailed description of the structure, activity, and potential applications of Anti-Mouse MMP3 Antibody (CH01).
Anti-Mouse MMP3 Antibody (CH01) is a monoclonal antibody, meaning it is derived from a single clone of immune cells. It is produced by hybridoma cells, which are created by fusing a specific type of immune cell with a cancer cell. This fusion results in a hybrid cell that has the ability to continuously produce large quantities of the desired antibody. The antibody has a molecular weight of approximately 150 kDa and is composed of two heavy chains and two light chains. The heavy chains are further divided into constant and variable regions, with the variable regions being responsible for binding to the target protein, MMP3.
The main function of Anti-Mouse MMP3 Antibody (CH01) is to specifically bind to MMP3 and inhibit its activity. This is achieved through the binding of the antibody’s variable regions to specific regions on the MMP3 protein, preventing it from carrying out its enzymatic function. MMP3 is known to play a crucial role in various physiological processes, such as tissue remodeling, wound healing, and angiogenesis. However, dysregulation of MMP3 has been linked to various diseases, including cancer, arthritis, and cardiovascular diseases. By inhibiting the activity of MMP3, Anti-Mouse MMP3 Antibody (CH01) has the potential to modulate these disease processes and provide therapeutic benefits.
Anti-Mouse MMP3 Antibody (CH01) has a wide range of potential applications in both research and therapeutic settings. In research, the antibody can be used as a tool to study the role of MMP3 in various disease processes. It can also be used in experiments to validate the efficacy of potential MMP3 inhibitors. In addition, Anti-Mouse MMP3 Antibody (CH01) can be used in diagnostic assays to measure the levels of MMP3 in biological samples, providing valuable information about disease progression and response to treatment.
In terms of therapeutic applications, Anti-Mouse MMP3 Antibody (CH01) has the potential to be used as a targeted therapy for diseases where MMP3 is dysregulated. For example, in cancer, MMP3 has been shown to promote tumor growth and metastasis. By inhibiting MMP3 activity, Anti-Mouse MMP3 Antibody (CH01) could potentially slow down tumor growth and prevent metastasis. In addition, MMP3 has been implicated in the progression of arthritis by promoting cartilage degradation. Anti-Mouse MMP3 Antibody (CH01) could potentially be used to slow down the progression of arthritis and alleviate symptoms.
In summary, Anti-Mouse MMP3 Antibody (CH01) is a highly specific and potent monoclonal antibody that targets the MMP3 protein in mice. Its structure, activity, and potential applications make it a valuable tool for both research and therapeutic purposes. With further studies and development, Anti-Mouse MMP3 Antibody (CH01) has the potential to be a promising therapeutic agent for diseases where MMP3 is dysregulated, providing new treatment options for patients.
ProteoGenix catalogue number ARO-A15080. For research use only.
Target: Anti-Human, Mouse, Rat Monoclonal Antibody; Host: Rat; Clonality: Monoclonal Antibody; Reactivity: Anti-Human, Mouse, Rat Monoclonal Antibody, Human, Mouse, Rat; Applications: ELISA, IF/ICC, Flow Cyt.
Available configurations: 50ug, 100ug, 1mg.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Species | WB | IHC-P | IHC-Fr | IF/ICC | Flow Cyt | IP | ChIP | ELISA |
|---|---|---|---|---|---|---|---|---|
| Anti-Human, Mouse, Rat Monoclonal Antibody | ||||||||
| Human | ||||||||
| Mouse | ||||||||
| Rat |
This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
Matrix metallopeptidase 3 (MMP3), also known as matrix metalloproteinase-3 or stromelysin-1, is a secreted extracellular-matrix protease. This ABMIUM record connects NCBI Gene 4314 and UniProtKB P08254 to catalogue-backed research products.
Biological function: Matrix metallopeptidase 3 (MMP3/stromelysin-1) is a zinc-dependent extracellular protease with broad substrate specificity. It can degrade multiple extracellular-matrix components, including fibronectin and laminin, and can process or activate other proteins including matrix metalloproteinases.
