Manufactured by:ProteoGenix
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Anti-Mouse MLKL Polyclonal Antibody

Anti-Mouse MLKL Polyclonal Antibody from ProteoGenix; catalogue ARO-A22155; research use only.

SKU:
ABM121613-1
Manufacturer SKU
ARO-A22155
Product type
Primary Antibodies
TargetMixed lineage kinase domain-like protein; Mlkl
ApplicationsELISA, IHC
Species / reactivityMouse

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Anti-Mouse MLKL Polyclonal Antibody: A Powerful Tool for Studying Cell Death Mechanisms

The Anti-Mouse MLKL Polyclonal Antibody is a highly specific and sensitive tool for studying cell death mechanisms in a variety of biological systems. This antibody targets the Mouse Mixed Lineage Kinase Domain-Like (MLKL) protein, which plays a crucial role in the regulation of necroptosis, a form of programmed cell death.

Biological Function:

MLKL is a key protein involved in the necroptosis signaling pathway, which is a type of programmed cell death that is distinct from apoptosis. This pathway is activated in response to cellular stress and plays a critical role in immune response, inflammation, and tissue development. MLKL is responsible for the execution of necroptosis by forming pores in the cell membrane, leading to cell death.

Main Applications:

The Anti-Mouse MLKL Polyclonal Antibody is a valuable tool for researchers studying necroptosis and its role in various biological processes. This antibody is particularly useful for investigating the molecular mechanisms of necroptosis and its potential involvement in diseases such as cancer, neurodegeneration, and autoimmune disorders. Additionally, this antibody can be used for immunohistochemistry, Western blotting, and flow cytometry applications.

Experimental Use Cases:

The Anti-Mouse MLKL Polyclonal Antibody has been extensively validated in various experimental models, including cell culture systems and animal models. In one study, this antibody was used to demonstrate the role of MLKL in the induction of necroptosis in response to viral infection. In another study, the antibody was used to investigate the involvement of necroptosis in the development of inflammatory bowel disease.

Short

Why Choose the Anti-Mouse MLKL Polyclonal Antibody?

  • Highly specific and sensitive: The antibody specifically targets MLKL, ensuring reliable and accurate results.
  • Wide range of applications: This antibody can be used for various techniques, making it a versatile tool for researchers.
  • Extensively validated: The antibody has been validated in multiple experimental systems, ensuring its reliability and reproducibility.
  • Expertly designed: Our team of scientists has carefully designed and optimized this antibody to provide the best possible results.

Ordering Information

To order the Anti-Mouse MLKL Polyclonal Antibody, please visit our website or contact our customer service team. We offer a variety of sizes and formats to suit your research needs. Our products are shipped with detailed datasheets and protocols to ensure successful experiments.

In conclusion, the Anti-Mouse MLKL Polyclonal Antibody is a powerful tool for studying cell death mechanisms, particularly necroptosis. With its high specificity, wide range of applications, and extensive validation, this antibody is a valuable addition to any researcher’s toolkit. Order now and uncover the mysteries of necroptosis with confidence.

ProteoGenix catalogue number ARO-A22155. For research use only.

Target: Mixed lineage kinase domain-like protein; Mlkl; Clonality: Polyclonal Antibody; Reactivity: Mouse; Applications: ELISA, IHC.

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Key facts & specifications
Clonality
Polyclonal
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation

Evidence status by application and model.

SpeciesWBIHC-PIHC-FrIF/ICCFlow CytIPChIPELISAIHC
Mouse
Identifiers & database references
Manufacturer SKU
ARO-A22155
Storage, stability & shipping
Storage conditions
4°C for short term (1 week), store at -20°C to -80°C for long term(1 year); Avoid repeated freeze-thaw cycles
Shipped at
Blue ice (+4°C)
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
£185.00£148.00