Anti IL1RL1, ST2 Biosimilar – Anti-IL1RL1, ST2 mAb – Research Grade from ProteoGenix; catalogue PX-TA1634; research use only.
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Title: Understanding the Structure and Function of Anti IL1RL1, ST2 Biosimilar – Anti-IL1RL1, ST2 mAb
Anti IL1RL1, ST2 is a biosimilar antibody that targets the interleukin-1 receptor-like 1 (IL1RL1) and ST2 protein. This protein is a member of the interleukin-1 receptor family and has been identified as a potential therapeutic target for various inflammatory and autoimmune diseases. In this article, we will discuss the structure, activity, and potential applications of Anti IL1RL1, ST2 Biosimilar – Anti-IL1RL1, ST2 mAb.
Anti IL1RL1, ST2 Biosimilar – Anti-IL1RL1, ST2 mAb is a monoclonal antibody (mAb) that is produced by recombinant DNA technology. It is a fully humanized antibody, meaning it is derived from human cells and has a lower risk of causing an immune response in patients. The antibody has a molecular weight of approximately 150 kDa and is composed of two heavy chains and two light chains. The heavy chains contain the antigen-binding region, which is responsible for binding to the IL1RL1, ST2 protein.
The main activity of Anti IL1RL1, ST2 Biosimilar – Anti-IL1RL1, ST2 mAb is to bind to the IL1RL1, ST2 protein and block its function. IL1RL1, ST2 is a receptor for the cytokine interleukin-33 (IL-33), which is involved in various inflammatory and immune responses. By blocking the interaction between IL-33 and IL1RL1, ST2, Anti IL1RL1, ST2 Biosimilar – Anti-IL1RL1, ST2 mAb can inhibit the downstream signaling pathways and reduce inflammation in the body.
Anti IL1RL1, ST2 Biosimilar – Anti-IL1RL1, ST2 mAb has shown promising results in preclinical studies and is currently being evaluated in clinical trials for the treatment of various inflammatory and autoimmune diseases. Some of the potential applications of this biosimilar antibody include:
1. Asthma: IL1RL1, ST2 has been identified as a biomarker for asthma and is involved in the pathogenesis of the disease. By blocking the IL-33/IL1RL1, ST2 pathway, Anti IL1RL1, ST2 Biosimilar – Anti-IL1RL1, ST2 mAb can potentially reduce airway inflammation and improve asthma symptoms.
2. Atopic dermatitis: IL-33 and IL1RL1, ST2 have been implicated in the development of atopic dermatitis, a chronic inflammatory skin disease. Anti IL1RL1, ST2 Biosimilar – Anti-IL1RL1, ST2 mAb may be able to alleviate symptoms of atopic dermatitis by blocking the IL-33/IL1RL1, ST2 signaling pathway.
3. Rheumatoid arthritis: IL-33 has been shown to play a role in the pathogenesis of rheumatoid arthritis, a chronic autoimmune disease. By targeting IL1RL1, ST2, Anti IL1RL1, ST2 Biosimilar – Anti-IL1RL1, ST2 mAb may be able to reduce joint inflammation and slow down the progression of the disease.
4. Inflammatory bowel disease (IBD): IL-33 and IL1RL1, ST2 have been implicated in the development of IBD, including Crohn’s disease and ulcerative colitis. Anti IL1RL1, ST2 Biosimilar – Anti-IL1RL1, ST2 mAb may be able to reduce intestinal inflammation and improve symptoms in patients with IBD.
ProteoGenix catalogue number PX-TA1634. For research use only.
Target: IL1RL1, ST2 Biosimilar – Anti-IL1RL1, ST2 mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: Mammalian cells; Purity: >85%; Buffer: PBS buffer PH7.5; Applications: ELISA, WB.
Available configurations: 50ug, 100ug, 1mg.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Target | WB | IHC-P | IHC-Fr | IF/ICC | Flow Cyt | IP | ChIP | ELISA |
|---|---|---|---|---|---|---|---|---|
| IL1RL1, ST2 Biosimilar – Anti-IL1RL1, ST2 mAb – Research Grade |
This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.