Manufactured by:ProteoGenix
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Anti IL1RL1, ST2 Biosimilar – Anti-IL1RL1, ST2 mAb – Research Grade

Anti IL1RL1, ST2 Biosimilar – Anti-IL1RL1, ST2 mAb – Research Grade from ProteoGenix; catalogue PX-TA1634; research use only.

SKU:
ABM134412-1
Manufacturer SKU
PX-TA1634
Product type
Primary Antibodies
TargetIL1RL1, ST2 Biosimilar – Anti-IL1RL1, ST2 mAb – Research Grade
ApplicationsELISA, WB
Expression systemMammalian cells
Purity>85%

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Title: Understanding the Structure and Function of Anti IL1RL1, ST2 Biosimilar – Anti-IL1RL1, ST2 mAb

Introduction

Anti IL1RL1, ST2 is a biosimilar antibody that targets the interleukin-1 receptor-like 1 (IL1RL1) and ST2 protein. This protein is a member of the interleukin-1 receptor family and has been identified as a potential therapeutic target for various inflammatory and autoimmune diseases. In this article, we will discuss the structure, activity, and potential applications of Anti IL1RL1, ST2 Biosimilar – Anti-IL1RL1, ST2 mAb.

Structure of Anti IL1RL1, ST2 Biosimilar – Anti-IL1RL1, ST2 mAb

Anti IL1RL1, ST2 Biosimilar – Anti-IL1RL1, ST2 mAb is a monoclonal antibody (mAb) that is produced by recombinant DNA technology. It is a fully humanized antibody, meaning it is derived from human cells and has a lower risk of causing an immune response in patients. The antibody has a molecular weight of approximately 150 kDa and is composed of two heavy chains and two light chains. The heavy chains contain the antigen-binding region, which is responsible for binding to the IL1RL1, ST2 protein.

Activity of Anti IL1RL1, ST2 Biosimilar – Anti-IL1RL1, ST2 mAb

The main activity of Anti IL1RL1, ST2 Biosimilar – Anti-IL1RL1, ST2 mAb is to bind to the IL1RL1, ST2 protein and block its function. IL1RL1, ST2 is a receptor for the cytokine interleukin-33 (IL-33), which is involved in various inflammatory and immune responses. By blocking the interaction between IL-33 and IL1RL1, ST2, Anti IL1RL1, ST2 Biosimilar – Anti-IL1RL1, ST2 mAb can inhibit the downstream signaling pathways and reduce inflammation in the body.

Applications of Anti IL1RL1, ST2 Biosimilar – Anti-IL1RL1, ST2 mAb

Anti IL1RL1, ST2 Biosimilar – Anti-IL1RL1, ST2 mAb has shown promising results in preclinical studies and is currently being evaluated in clinical trials for the treatment of various inflammatory and autoimmune diseases. Some of the potential applications of this biosimilar antibody include:

1. Asthma: IL1RL1, ST2 has been identified as a biomarker for asthma and is involved in the pathogenesis of the disease. By blocking the IL-33/IL1RL1, ST2 pathway, Anti IL1RL1, ST2 Biosimilar – Anti-IL1RL1, ST2 mAb can potentially reduce airway inflammation and improve asthma symptoms.

2. Atopic dermatitis: IL-33 and IL1RL1, ST2 have been implicated in the development of atopic dermatitis, a chronic inflammatory skin disease. Anti IL1RL1, ST2 Biosimilar – Anti-IL1RL1, ST2 mAb may be able to alleviate symptoms of atopic dermatitis by blocking the IL-33/IL1RL1, ST2 signaling pathway.

3. Rheumatoid arthritis: IL-33 has been shown to play a role in the pathogenesis of rheumatoid arthritis, a chronic autoimmune disease. By targeting IL1RL1, ST2, Anti IL1RL1, ST2 Biosimilar – Anti-IL1RL1, ST2 mAb may be able to reduce joint inflammation and slow down the progression of the disease.

4. Inflammatory bowel disease (IBD): IL-33 and IL1RL1, ST2 have been implicated in the development of IBD, including Crohn’s disease and ulcerative colitis. Anti IL1RL1, ST2 Biosimilar – Anti-IL1RL1, ST2 mAb may be able to reduce intestinal inflammation and improve symptoms in patients with IBD.

ProteoGenix catalogue number PX-TA1634. For research use only.

Target: IL1RL1, ST2 Biosimilar – Anti-IL1RL1, ST2 mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: Mammalian cells; Purity: >85%; Buffer: PBS buffer PH7.5; Applications: ELISA, WB.

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Key facts & specifications
Also known as
Anti IL1RL1, ST2,,IL1RL1, ST2,anti-IL1RL1, ST2
Clonality
Monoclonal
Isotype
Human IgG
Source organism
Humanized
Technical note
For research use only. Not suitable for clinical or therapeutic use.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation

Evidence status by application and model.

TargetWBIHC-PIHC-FrIF/ICCFlow CytIPChIPELISA
IL1RL1, ST2 Biosimilar – Anti-IL1RL1, ST2 mAb – Research Grade
Identifiers & database references
Manufacturer SKU
PX-TA1634
Storage, stability & shipping
Storage conditions
store at -80°C
Shipped at
Blue ice (+4°C)
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
£139.00£111.20