Manufactured by:ProteoGenix
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Anti-Human XIAP/BIRC3 Polyclonal Antibody

Anti-Human XIAP/BIRC3 Polyclonal Antibody from ProteoGenix; catalogue ARO-A21980; research use only.

SKU:
ABM121768-1
Manufacturer SKU
ARO-A21980
Product type
Primary Antibodies
TargetXIAP/BIRC3
ApplicationsIHC, ELISA
Species / reactivityHuman

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

Anti-Human XIAP/BIRC3 Polyclonal Antibody: A Powerful Tool for Cancer Research

The Anti-Human XIAP/BIRC3 Polyclonal Antibody is a highly specific and effective tool for cancer research. This antibody targets the X-linked inhibitor of apoptosis protein (XIAP) and the baculoviral inhibitor of apoptosis repeat-containing protein 3 (BIRC3), both of which are key players in the regulation of cell death and survival.

Biological Function:

XIAP and BIRC3 are members of the inhibitor of apoptosis (IAP) protein family, which are known to inhibit programmed cell death or apoptosis. These proteins play a crucial role in the development and progression of cancer by promoting cell survival and resistance to chemotherapy. The Anti-Human XIAP/BIRC3 Polyclonal Antibody binds to these proteins, neutralizing their anti-apoptotic effects and allowing for targeted cancer cell death.

Main Applications:

The Anti-Human XIAP/BIRC3 Polyclonal Antibody is a valuable tool for cancer research, with a wide range of applications including:

1. Studying the role of XIAP and BIRC3 in cancer development and progression
2. Evaluating the effectiveness of anti-cancer therapies targeting XIAP and BIRC3
3. Identifying potential biomarkers for cancer diagnosis and prognosis
4. Assessing the sensitivity of cancer cells to apoptosis-inducing agents
5. Investigating the mechanisms of drug resistance in cancer cells

Experimental Use Cases:

The Anti-Human XIAP/BIRC3 Polyclonal Antibody has been successfully used in various experimental settings, including:

1. Western blotting: The antibody has been used to detect XIAP and BIRC3 proteins in cell lysates, providing valuable insights into their expression levels and post-translational modifications.
2. Immunofluorescence: By labeling XIAP and BIRC3 in cancer cells, the antibody allows for visualization and localization of these proteins, aiding in the study of their subcellular distribution and function.
3. Flow cytometry: The antibody has been used to analyze the expression of XIAP and BIRC3 in different cell populations, providing valuable information on their role in cancer cell heterogeneity.
4. Immunohistochemistry: The antibody has been used to assess the expression of XIAP and BIRC3 in tissue samples, allowing for the identification of potential therapeutic targets in various types of cancer.

In all these applications, the Anti-Human XIAP/BIRC3 Polyclonal Antibody has demonstrated high specificity and sensitivity, making it a trusted tool for cancer researchers.

Conclusion:

The Anti-Human XIAP/BIRC3 Polyclonal Antibody is a powerful tool for cancer research, with a well-defined biological function and a wide range of applications. By targeting XIAP and BIRC3, this antibody allows for a deeper understanding of their role in cancer and provides valuable insights for the development of new therapeutic strategies. Choose this antibody for reliable and accurate results in your cancer research.

ProteoGenix catalogue number ARO-A21980. For research use only.

Target: XIAP/BIRC3; Clonality: Polyclonal Antibody; Reactivity: Human; Applications: IHC, ELISA.

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Key facts & specifications
Also known as
Anti-E3 ubiquitin-protein ligase XIAP, 2.3.2.27, Baculoviral IAP repeat-containing protein 4, IAP-like protein, ILP, hILP, Inhibitor of apoptosis protein 3, IAP-3, hIAP-3, hIAP3, RING-type E3 ubiquitin transferase XIAP, X-linked inhibitor of apoptosis protein, X-linked IAP, XIAP, API3, BIRC4, IAP3
Clonality
Polyclonal
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation

Evidence status by application and model.

SpeciesWBIHC-PIHC-FrIF/ICCFlow CytIPChIPELISAIHC
Human
Identifiers & database references
Manufacturer SKU
ARO-A21980
Storage, stability & shipping
Storage conditions
4°C for short term (1 week), store at -20°C to -80°C for long term(1 year); Avoid repeated freeze-thaw cycles
Shipped at
Blue ice (+4°C)
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
£189.00£151.20