Anti-Human XIAP/BIRC3 Polyclonal Antibody from ProteoGenix; catalogue ARO-A21980; research use only.
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Anti-Human XIAP/BIRC3 Polyclonal Antibody: A Powerful Tool for Cancer Research
The Anti-Human XIAP/BIRC3 Polyclonal Antibody is a highly specific and effective tool for cancer research. This antibody targets the X-linked inhibitor of apoptosis protein (XIAP) and the baculoviral inhibitor of apoptosis repeat-containing protein 3 (BIRC3), both of which are key players in the regulation of cell death and survival.
XIAP and BIRC3 are members of the inhibitor of apoptosis (IAP) protein family, which are known to inhibit programmed cell death or apoptosis. These proteins play a crucial role in the development and progression of cancer by promoting cell survival and resistance to chemotherapy. The Anti-Human XIAP/BIRC3 Polyclonal Antibody binds to these proteins, neutralizing their anti-apoptotic effects and allowing for targeted cancer cell death.
The Anti-Human XIAP/BIRC3 Polyclonal Antibody is a valuable tool for cancer research, with a wide range of applications including:
1. Studying the role of XIAP and BIRC3 in cancer development and progression
2. Evaluating the effectiveness of anti-cancer therapies targeting XIAP and BIRC3
3. Identifying potential biomarkers for cancer diagnosis and prognosis
4. Assessing the sensitivity of cancer cells to apoptosis-inducing agents
5. Investigating the mechanisms of drug resistance in cancer cells
The Anti-Human XIAP/BIRC3 Polyclonal Antibody has been successfully used in various experimental settings, including:
1. Western blotting: The antibody has been used to detect XIAP and BIRC3 proteins in cell lysates, providing valuable insights into their expression levels and post-translational modifications.
2. Immunofluorescence: By labeling XIAP and BIRC3 in cancer cells, the antibody allows for visualization and localization of these proteins, aiding in the study of their subcellular distribution and function.
3. Flow cytometry: The antibody has been used to analyze the expression of XIAP and BIRC3 in different cell populations, providing valuable information on their role in cancer cell heterogeneity.
4. Immunohistochemistry: The antibody has been used to assess the expression of XIAP and BIRC3 in tissue samples, allowing for the identification of potential therapeutic targets in various types of cancer.
In all these applications, the Anti-Human XIAP/BIRC3 Polyclonal Antibody has demonstrated high specificity and sensitivity, making it a trusted tool for cancer researchers.
Conclusion:
The Anti-Human XIAP/BIRC3 Polyclonal Antibody is a powerful tool for cancer research, with a well-defined biological function and a wide range of applications. By targeting XIAP and BIRC3, this antibody allows for a deeper understanding of their role in cancer and provides valuable insights for the development of new therapeutic strategies. Choose this antibody for reliable and accurate results in your cancer research.
ProteoGenix catalogue number ARO-A21980. For research use only.
Target: XIAP/BIRC3; Clonality: Polyclonal Antibody; Reactivity: Human; Applications: IHC, ELISA.
Available configurations: 50ug, 100ug, 1mg.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Species | WB | IHC-P | IHC-Fr | IF/ICC | Flow Cyt | IP | ChIP | ELISA | IHC |
|---|---|---|---|---|---|---|---|---|---|
| Human |
This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.