Manufactured by:ProteoGenix
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Anti-Human PODXL Polyclonal Antibody

Anti-Human PODXL Polyclonal Antibody from ProteoGenix; catalogue ARO-A22000; research use only.

SKU:
ABM121752-1
Manufacturer SKU
ARO-A22000
Product type
Primary Antibodies
TargetPODXL
ApplicationsELISA, WB, IHC
Species / reactivityHuman

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Anti-Human PODXL Polyclonal Antibody: A Powerful Tool for Targeting Cancer Cells

Introduction:

The Anti-Human PODXL Polyclonal Antibody is a highly specific and effective tool for researchers studying cancer and its progression. This antibody targets podocalyxin-like protein (PODXL), a glycoprotein that is overexpressed in many types of cancer cells. With its ability to bind to PODXL, this antibody can be used for a variety of applications in cancer research.

Biological Function:

PODXL is a transmembrane protein that plays a crucial role in cell adhesion, migration, and invasion. In cancer cells, it is often upregulated and contributes to the aggressive behavior of tumors. By targeting PODXL, the Anti-Human PODXL Polyclonal Antibody can inhibit the functions of this protein, leading to decreased cancer cell migration and invasion.

Main Applications:

This antibody has been widely used in cancer research for its ability to specifically target and inhibit PODXL. It can be used in immunohistochemistry, western blotting, and flow cytometry to detect and quantify PODXL expression in cancer cells. Additionally, this antibody can be used in functional studies to investigate the role of PODXL in cancer progression.

Experimental Use Cases:

1. Detecting PODXL expression in cancer tissues: The Anti-Human PODXL Polyclonal Antibody can be used in immunohistochemistry to detect the expression of PODXL in cancer tissues. This can provide valuable information on the presence and distribution of PODXL in different types of cancer.

2. Inhibiting cancer cell migration and invasion: By targeting and binding to PODXL, this antibody can inhibit the functions of this protein, leading to decreased cancer cell migration and invasion. This can be studied using functional assays such as wound healing and invasion assays.

3. Investigating the role of PODXL in cancer progression: The Anti-Human PODXL Polyclonal Antibody can be used in knockdown or overexpression experiments to study the effects of PODXL on cancer cell behavior. This can provide insights into the mechanisms of cancer progression and identify potential therapeutic targets.

Conclusion:

The Anti-Human PODXL Polyclonal Antibody is a valuable tool for cancer research, offering a specific and effective way to target and study PODXL. With its multiple applications and experimental use cases, this antibody can provide valuable insights into the role of PODXL in cancer progression. Order now and take your cancer research to the next level.

ProteoGenix catalogue number ARO-A22000. For research use only.

Target: PODXL; Clonality: Polyclonal Antibody; Reactivity: Human; Applications: ELISA, WB, IHC.

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Key facts & specifications
Also known as
Anti-Podocalyxin, GCTM-2 antigen, Gp200, Podocalyxin-like protein 1, PC, PCLP-1, PODXL
Clonality
Polyclonal
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation

Evidence status by application and model.

SpeciesWBIHC-PIHC-FrIF/ICCFlow CytIPChIPELISAIHC
Human
Identifiers & database references
Manufacturer SKU
ARO-A22000
Storage, stability & shipping
Storage conditions
4°C for short term (1 week), store at -20°C to -80°C for long term(1 year); Avoid repeated freeze-thaw cycles
Shipped at
Blue ice (+4°C)
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
£195.00£156.00