Anti-Human APH1A Polyclonal Antibody from ProteoGenix; catalogue ARO-A22078; research use only.
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The Anti-Human APH1A Polyclonal Antibody is a powerful tool for researchers in the biotech industry. This antibody is specifically designed to target the APH1A protein, which plays a crucial role in the Notch signaling pathway.
The Notch signaling pathway is a highly conserved mechanism that regulates cell fate determination, cell proliferation, and cell differentiation. Dysregulation of this pathway has been linked to various diseases, including cancer, cardiovascular diseases, and neurological disorders.
This polyclonal antibody is highly specific and sensitive, allowing for accurate detection and quantification of APH1A in various biological samples. It has been extensively validated for use in Western blotting, immunohistochemistry, and immunofluorescence experiments.
One of the main applications of the Anti-Human APH1A Polyclonal Antibody is in cancer research. Studies have shown that APH1A is overexpressed in many types of cancer, making it a potential therapeutic target. This antibody can be used to study the expression levels of APH1A in cancer cells and tissues, providing valuable insights into the development and progression of the disease.
Furthermore, this antibody has also been used in cardiovascular research to investigate the role of APH1A in heart development and function. It has been shown to be essential for proper heart development and function, and its dysregulation has been linked to various cardiovascular diseases.
In addition to cancer and cardiovascular research, the Anti-Human APH1A Polyclonal Antibody has also been used in studies related to neurological disorders. APH1A has been found to play a crucial role in the development and function of the central nervous system, and its dysfunction has been linked to diseases such as Alzheimer’s and Parkinson’s.
In summary, the Anti-Human APH1A Polyclonal Antibody is a valuable tool for researchers studying the Notch signaling pathway and its role in various diseases. Its high specificity and sensitivity, along with its various applications, make it a versatile and essential antibody in the biotech industry. Order now to advance your research and gain a deeper understanding of APH1A and its biological functions.
ProteoGenix catalogue number ARO-A22078. For research use only.
Target: Gamma-secretase subunit APH-1A; APH-1a; Aph-1alpha; Presenilin-stabilization factor; APH1A; PSF; CGI-78; UNQ579/PRO1141; Clonality: Polyclonal Antibody; Reactivity: Human; Applications: IHC, ELISA.
Available configurations: 50ug, 100ug, 1mg.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Species | WB | IHC-P | IHC-Fr | IF/ICC | Flow Cyt | IP | ChIP | ELISA | IHC |
|---|---|---|---|---|---|---|---|---|---|
| Human |
This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
