Anti-DBT Polyclonal Antibody from ProteoGenix; catalogue ARO-A22079; research use only.
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Anti-DBT Polyclonal Antibody
Anti-DBT Polyclonal Antibody is a high-quality antibody that specifically targets the dihydroxyacetone phosphate acyltransferase (DBT) protein. DBT is an essential enzyme involved in the breakdown of amino acids, specifically the branched-chain amino acids (BCAAs) leucine, isoleucine, and valine. This antibody binds to DBT and inhibits its activity, leading to a decrease in BCAA metabolism.
This antibody is primarily used in research studies to investigate the role of DBT in various biological processes. It has been shown to be effective in studying BCAA metabolism, as well as its involvement in diseases such as maple syrup urine disease and liver cirrhosis. Additionally, this antibody can be used in diagnostic assays to detect changes in DBT levels, providing valuable insights into metabolic disorders.
Anti-DBT Polyclonal Antibody has been successfully used in various experimental settings. In one study, it was used to investigate the effects of DBT inhibition on cancer cell growth and survival. The results showed that blocking DBT activity with this antibody led to a significant decrease in cancer cell proliferation. In another study, this antibody was used to explore the role of DBT in muscle metabolism and its potential as a therapeutic target for muscle-wasting diseases.
With its high specificity and sensitivity, this antibody has also been used in immunohistochemistry and Western blotting techniques to detect DBT expression in tissue samples. These experiments have provided valuable insights into the localization and expression patterns of DBT in different tissues and organs.
In summary, Anti-DBT Polyclonal Antibody is a valuable tool for researchers studying BCAA metabolism and its implications in various diseases. Its versatility and reliability make it a crucial component in the investigation of DBT function and its potential as a therapeutic target. Choose this antibody for accurate and reproducible results in your experiments.
Keywords: Anti-DBT Polyclonal Antibody, dihydroxyacetone phosphate acyltransferase, BCAAs, metabolic disorders, cancer cell growth, muscle metabolism, immunohistochemistry, Western blotting, therapeutic target, research studies.
ProteoGenix catalogue number ARO-A22079. For research use only.
Target: Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial; 2.3.1.168; 52 kDa mitochondrial autoantigen of primary biliary cirrhosis; Branched chain 2-oxo-acid dehydrogenase complex component E2; BCOADC-E2; Branched-chain alpha-keto acid dehydrogenase complex component E2; BCKAD-E2; BCKADE2; BCKDH-E2; Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex; Dihydrolipoamide branched chain transacylase; Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase; DBT; BCATE2; BCKDHE2; Clonality: Polyclonal Antibody; Applications: ELISA, IHC.
Available configurations: 50ug, 100ug, 1mg.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Target | WB | IHC-P | IHC-Fr | IF/ICC | Flow Cyt | IP | ChIP | ELISA | IHC |
|---|---|---|---|---|---|---|---|---|---|
| Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial; 2.3.1.168; 52 kDa mitochondrial autoantigen of primary biliary cirrhosis; Branched chain 2-oxo-acid dehydrogenase complex component E2; BCOADC-E2; Branched-chain alpha-keto acid dehydrogenase complex component E2; BCKAD-E2; BCKADE2; BCKDH-E2; Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex; Dihydrolipoamide branched chain transacylase; Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase; DBT; BCATE2; BCKDHE2 |
This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
