Kit ELISA fourni par Boster Bio
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L'interleukine-2 (IL2), anciennement appelée facteur de croissance des lymphocytes T, est une lymphokine à puissant pouvoir immunorégulateur, produite par les lymphocytes T activés par des lectines ou des antigènes. Elle est produite non seulement par les lymphocytes T matures lors de la stimulation, mais aussi de manière constitutive par certaines lignées cellulaires de lymphomes T. L'interleukine-2 (IL-2) est responsable de la progression du cycle cellulaire autocrine et de la régulation des réponses immunitaires. L'expression de l'IL-2 dans les thymocytes matures et les lymphocytes T s'est avérée être étroitement contrôlée par une expression monoallélique. L'IL-2 peut agir comme une hormone de croissance pour les lymphocytes B et T. Le gène humain de l'interleukine 2 (IL2) est situé sur le chromosome 4. L'IL-2 de souris contient 149 acides aminés sous forme mature, avec une masse moléculaire de 17,2 kDa.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Sample compatibility evidence using the same validation key.
| Sample type | Compatibilité de l'échantillon | Gamme de test | Sensibilité | Spécificité |
|---|---|---|---|---|
| surnageants de culture cellulaire | ||||
| sérum | ||||
| plasma (héparine | ||||
| EDTA) |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
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Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
IL2 identifies interleukin 2 in Homo sapiens (Human). This target record connects NCBI Gene 3558, UniProtKB P60568 and related ABMIUM catalogue products.
Biological function: IL2 is a cytokine produced mainly by activated T cells that supports immune-cell proliferation, differentiation and survival. It signals through IL2 receptor complexes to activate JAK-STAT, PI3K and MAPK pathways, supporting T-cell, regulatory T-cell, NK-cell and B-cell responses.
