Kit ELISA fourni par Boster Bio
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Le facteur de croissance des fibroblastes 23 ou FGF23 est une protéine qui, chez l'homme, est encodée par le gène FGF23. C'est un membre de la famille des facteurs de croissance des fibroblastes (FGF) qui est responsable du métabolisme du phosphate. La fonction principale du FGF23 semble être la régulation de la concentration de phosphate dans le plasma. Le FGF23 est sécrété par les ostéocytes en réponse à une élévation du Calcitriol. Et il agit sur les reins, où il diminue l'expression de NPT2, un cotransporteur sodium-phosphate dans le tubule proximal. Ainsi, le FGF23 diminue la réabsorption et augmente l'excrétion du phosphate. De plus, le FGF23 peut supprimer la 1-alpha-hydroxylase, réduisant sa capacité à activer la vitamine D et altérant par conséquent l'absorption du calcium.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Sample compatibility evidence using the same validation key.
| Sample type | Compatibilité de l'échantillon | Gamme de test | Sensibilité | Spécificité |
|---|---|---|---|---|
| surnageants de culture cellulaire | ||||
| lysats cellulaires | ||||
| sérum et plasma (héparine | ||||
| EDTA). |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
FGF23 identifies fibroblast growth factor 23 in Homo sapiens (Human). This target record connects NCBI Gene 8074, UniProtKB Q9GZV9 and related ABMIUM catalogue products.
