Kit ELISA fourni par Boster Bio
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La dipeptidyl peptidase-4 (DPP4), également connue sous le nom de protéine complexante de l'adénosine désaminase 2 ou CD26 (cluster de différenciation 26), est une protéine qui, chez l'homme, est codée par le gène DPP4. Par hybridation in situ en fluorescence, le gène CD26 a été cartographié en 2q24.3. La DPP4 joue un rôle majeur dans le métabolisme du glucose. Elle est responsable de la dégradation des incrétines telles que le GLP-1. De plus, elle semble agir comme un suppresseur dans le développement du cancer et des tumeurs. Le CD26/DPP4 joue un rôle important dans la biologie tumorale et est utile en tant que marqueur pour divers cancers, avec des niveaux soit à la surface cellulaire, soit dans le sérum, augmentés dans certaines néoplasies et diminués dans d'autres.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Sample compatibility evidence using the same validation key.
| Sample type | Compatibilité de l'échantillon | Gamme de test | Sensibilité | Spécificité |
|---|---|---|---|---|
| surnageants de culture cellulaire | ||||
| lysats cellulaires | ||||
| sérum et plasma (héparine | ||||
| EDTA). |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
DPP4 identifies dipeptidyl peptidase 4 in Homo sapiens (Human). This target record connects NCBI Gene 1803, UniProtKB P27487 and related ABMIUM catalogue products.
Biological function: Dipeptidyl peptidase 4 (DPP4; CD26/DPP IV) is a type II transmembrane serine peptidase that removes N-terminal dipeptides from susceptible peptides and also functions as a cell-surface signalling and costimulatory protein. It is studied in incretin metabolism, glucose homeostasis and immune regulation.
