Kit ELISA fourni par Boster Bio
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L'apolipoprotéine H (Apo-H), anciennement connue sous le nom de β2-glycoprotéine I et bêta-2 glycoprotéine I, est une apolipoprotéine multifonctionnelle de 38 kDa qui, chez l'homme, est codée par le gène APOH. Ce gène est situé en 11 E1 ; 11 71,8 Cm. L'apolipoprotéine H a été impliquée dans diverses voies physiologiques, notamment le métabolisme des lipoprotéines, la coagulation et la production d'auto-anticorps antiphospholipides. L'APOH pourrait être un cofacteur requis pour la liaison des phospholipides anioniques par les auto-anticorps antiphospholipides trouvés dans le sérum de nombreux patients atteints de lupus et de syndrome des antiphospholipides primaire, mais elle ne semble pas être requise pour la réactivité des auto-anticorps antiphospholipides associés aux infections.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Sample compatibility evidence using the same validation key.
| Sample type | Compatibilité de l'échantillon | Gamme de test | Sensibilité | Spécificité |
|---|---|---|---|---|
| surnageants de culture cellulaire | ||||
| sérum et plasma (héparine | ||||
| EDTA). |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
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Apolipoprotein H (APOH), also known as beta-2-glycoprotein 1 (B2GPI), is a circulating plasma glycoprotein that associates with lipoproteins and anionic phospholipid surfaces. It is studied in lipoprotein metabolism, coagulation and antiphospholipid-antibody biology.
Biological function: APOH/beta-2-glycoprotein 1 is a plasma lipoprotein-associated glycoprotein with affinity for negatively charged phospholipid surfaces. NCBI describes roles and associations in lipoprotein metabolism, coagulation and hemostasis, and notes that beta-2-GPI can act as a cofactor for antiphospholipid autoantibody binding.
