Kit ELISA fourni par Boster Bio
Know who made it. See the evidence. Buy through one marketplace.
L'interleukine 33 (IL-33) est une cytokine appartenant à la superfamille de l'IL-1. Le gène IL33 est localisé sur le chromosome 9p24.1 par analyse de base de données génomique. L'IL33 humaine mature recombinante se lie à ST2. L'induction de cytokines de type 2 par l'IL-33 in vivo est censée induire les changements pathologiques graves observés dans les organes muqueux après l'administration d'IL-33. L'IL33, une alarmin libérée par les cellules nécrotiques, est nécessaire pour les réponses puissantes des lymphocytes T CD8+ (CTL) aux virus ARN et ADN réplicatifs et prototypiques chez la souris. L'IL33 a empêché la régulation négative de CXCR2 et l'inhibition de la chimiotaxie induites par l'activation de TLR4, et a constaté que l'IL33 inverse la réduction de l'expression de CXCR2 induite par TLR4 via l'inhibition de l'expression de GRK2.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Sample compatibility evidence using the same validation key.
| Sample type | Compatibilité de l'échantillon | Gamme de test | Sensibilité | Spécificité |
|---|---|---|---|---|
| surnageants de culture cellulaire | ||||
| sérum | ||||
| plasma (héparine | ||||
| EDTA) et lysats cellulaires. |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
IL33 identifies interleukin 33 in Homo sapiens (Human). This target record connects NCBI Gene 90865, UniProtKB O95760 and related ABMIUM catalogue products.
Biological function: IL33 is an IL-1 family cytokine that signals through IL1RL1/ST2, activating NF-kappa-B and MAPK pathways. It promotes type 2 immune responses and can activate mast cells, basophils, eosinophils and natural killer cells.
