Kit ELISA fourni par Boster Bio
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L'anhydrase carbonique 9 (CA9/CAIX) est une enzyme qui, chez l'homme, est codée par le gène CA9. Les anhydrases carboniques (AC) sont une grande famille de métalloprotéines à zinc qui catalysent l'hydratation réversible du dioxyde de carbone. Elles participent à une variété de processus biologiques, notamment la respiration, la calcification, l'équilibre acido-basique, la résorption osseuse et la formation de l'humeur aqueuse, du liquide céphalorachidien, de la salive et de l'acide gastrique. Ce gène est situé sur le chromosome 9p13.3. La CA IX est une protéine transmembranaire et la seule isoenzyme d'anhydrase carbonique associée à une tumeur connue. Elle est exprimée dans tous les carcinomes rénaux à cellules claires, mais n'est pas détectée dans les reins normaux ou la plupart des autres tissus normaux. Elle pourrait être impliquée dans la prolifération et la transformation cellulaire.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Sample compatibility evidence using the same validation key.
| Sample type | Compatibilité de l'échantillon | Gamme d'essai | Sensibilité | Spécificité |
|---|---|---|---|---|
| surnageants de culture cellulaire | ||||
| sérum | ||||
| plasma (héparine | ||||
| EDTA | ||||
| citrate) et urine. |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
Carbonic anhydrase 9 (CA9), also called carbonic anhydrase IX or CAIX, is a transmembrane zinc metalloenzyme involved in carbon dioxide/bicarbonate interconversion and pH regulation. ABMIUM catalogue products linked below support research on CA9 biology.
Biological function: Carbonic anhydrase 9 (CA9/CA IX/CAIX) is a transmembrane zinc-dependent carbonic anhydrase that catalyses the reversible interconversion of carbon dioxide and water with bicarbonate and hydrogen ions. Its expression is induced by hypoxia, linking CA9 to cellular acid-base regulation and hypoxia-associated research.
