Kit ELISA fourni par Boster Bio
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La bêta-2 microglobuline, également connue sous le nom de B2M, est un composant des molécules du CMH de classe I, présentes sur toutes les cellules nucléées (à l'exclusion des globules rouges). Chez l'homme, la protéine bêta-2-microglobuline est codée par le gène B2M. La protéine a une structure principalement en feuillet bêta plissé qui peut former des fibrilles amyloïdes dans certaines conditions pathologiques. La protéine antimicrobienne codée présente une activité antibactérienne dans le liquide amniotique. Il a été démontré qu'une mutation de ce gène entraîne une hypoprotéinémie hypercatabolique.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Sample compatibility evidence using the same validation key.
| Sample type | Compatibilité de l'échantillon | Gamme de test | Sensibilité | Spécificité |
|---|---|---|---|---|
| surnageants de culture cellulaire | ||||
| sérum | ||||
| plasma (héparine | ||||
| EDTA) | ||||
| salive | ||||
| urine et lait maternel |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
Beta-2-microglobulin (B2M, beta2-m) is the non-polymorphic light-chain component of major histocompatibility complex class I molecules. ABMIUM catalogue products linked below support research on B2M biology.
Biological function: Beta-2-microglobulin (B2M/beta2-m) associates non-covalently with major histocompatibility complex class I heavy chains and is required for stable MHC class I assembly and cell-surface expression. Through this role, B2M is integral to MHC-I antigen presentation and immune recognition by CD8-positive T cells.
