Anticorps polyclonal anti-ADA de lapin de chez ELK Biotechnology
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L'anticorps pAb de lapin anti-ADA est un anticorps ELK Biotechnology destiné aux flux de travail de recherche impliquant l'ADA.
Ce gène code pour une enzyme qui catalyse l'hydrolyse de l'adénosine en inosine. Diverses mutations ont été décrites pour ce gène et ont été liées à des maladies humaines. Une déficience de cette enzyme provoque une forme de maladie d'immunodéficience combinée sévère (SCID), dans laquelle il y a un dysfonctionnement des lymphocytes B et T avec une immunité cellulaire altérée et une production diminuée d'immunoglobulines, tandis que des niveaux élevés de cette enzyme ont été associés à une anémie hémolytique congénitale. [fourni par RefSeq, juillet 2008],
| Spécificité | L'anticorps polyclonal anti-ADA détecte les niveaux endogènes de protéine. |
|---|---|
| Légendes des preuves de validation | Analyse par Western blot de lysats de cellules K562, l'anticorps primaire a été dilué à 1:1000, 4° pendant la nuit |
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Espèce | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Humain | |||||||
| Rat | |||||||
| Souris |
This product is manufactured by ELK Biotechnology and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
Adenosine deaminase (ADA), also known as ADA1, is an enzyme of purine metabolism that deaminates adenosine and 2-deoxyadenosine. This ABMIUM target record links ADA biology, verified human identifiers and catalogue-backed research products.
Biological function: ADA catalyzes hydrolytic deamination of adenosine to inosine and 2-deoxyadenosine to deoxyinosine, helping regulate purine metabolism and adenosine homeostasis. Reviewed UniProt annotation also describes extracellular signalling roles associated with cell-surface ADA.
