CRADD lapin pAb de ELK Biotechnology
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L'anticorps pAb anti-CRADD est un anticorps d'ELK Biotechnology destiné aux flux de travail de recherche impliquant CRADD.
Ce gène code une protéine contenant un motif de domaine de mort (DD). Cette protéine recrute la caspase 2/ICH1 dans le complexe de transduction du signal de mort cellulaire, qui comprend le récepteur 1 du facteur de nécrose tumorale (TNFR1A) et la RIPK1/RIP kinase, et agit dans la promotion de l'apoptose. Une mutation dans ce gène a été associée au retard mental. Un pseudogène apparenté est trouvé sur le chromosome 3. L'épissage alternatif entraîne de multiples variants de transcrits. [fourni par RefSeq, Fév 2016]
| Spécificité | L'anticorps polyclonal CRADD détecte les niveaux endogènes de protéine. |
|---|---|
| Légendes des preuves de validation | Analyse par Western blot des lysats de cellules K562, l'anticorps primaire a été dilué à 1:1000, 4° pendant la nuit |
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Espèce | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Humain | |||||||
| Rat | |||||||
| Souris |
This product is manufactured by ELK Biotechnology and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.