CLUS lapin pAb de ELK Biotechnology
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L'anticorps polyclonal de lapin CLUS est un anticorps d'ELK Biotechnology destiné aux flux de travail de recherche impliquant CLUS.
La protéine encodée par ce gène est une protéine chaperonne sécrétée qui, dans certaines conditions de stress, peut également se trouver dans le cytosol cellulaire. Il a été suggéré qu'elle est impliquée dans plusieurs événements biologiques fondamentaux tels que la mort cellulaire, la progression tumorale et les troubles neurodégénératifs. L'épissage alternatif donne lieu à des variantes codantes et non codantes.[fourni par RefSeq, mai 2011],
| Spécificité | Cet anticorps détecte les niveaux endogènes de CLUS. |
|---|---|
| Légendes des preuves de validation | Analyse par Western blot du lysat MCF-7, l'anticorps a été dilué à 1000. L'anticorps secondaire (réf. catalogue : RS0002) a été dilué à 1:20000 |
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Espèce | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Humain | |||||||
| Souris | |||||||
| Rat |
This product is manufactured by ELK Biotechnology and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
Clusterin (CLU), also known as apolipoprotein J or ApoJ, is a secreted extracellular chaperone protein. This target guide connects human NCBI Gene 1191, UniProtKB P10909 and ABMIUM catalogue products associated with clusterin / CLU.
Biological function: Clusterin functions as an extracellular chaperone that helps prevent aggregation of non-native and stress-damaged proteins. The major secreted form can inhibit formation of several amyloid fibrils in vitro and maintain partially unfolded proteins in a state that can be handled by other chaperone systems.
