pAb de lapin anti-IGFBP6 de ELK Biotechnology
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L'anticorps polyclonal de lapin IGFBP6 est un anticorps d'ELK Biotechnology destiné aux flux de recherche impliquant l'IGFBP6.
Fonction : Les protéines de liaison à l'IGF prolongent la demi-vie des IGF et se sont avérées inhiber ou stimuler les effets de promotion de la croissance des IGF sur les cultures cellulaires. Elles modifient l'interaction des IGF avec leurs récepteurs de surface cellulaire., PTM : Les glycannes O-liés sont constitués de résidus hexose (probablement Gal), N-acétylhexosamine (probablement GalNAc) et acide sialique. Les principales glycoformes sont constituées de 8 à 16 monosaccharides (par homologie avec l'IGFBP6 exprimé de manière recombinante dans les cellules CHO)., Similitude : Contient 1 domaine N-terminal IGFBP., Similitude : Contient 1 domaine de type 1 thyroglobuline.,
| Spécificité | L'anticorps polyclonal IGFBP6 détecte les niveaux endogènes de la protéine IGFBP6. |
|---|---|
| Légendes des preuves de validation | Analyse par Western Blot de cellules K562 utilisant l'anticorps polyclonal IGFBP6. L'anticorps secondaire (catalogue n°: RS0002) a été dilué à 1:20000 | Analyse par Western blot de lysat de cellules K562, utilisant l'anticorps IGFBP6. |
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Espèce | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Humain | |||||||
| Rat | |||||||
| Souris |
This product is manufactured by ELK Biotechnology and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
IGFBP6 identifies insulin like growth factor binding protein 6 in Homo sapiens (Human). This target record connects NCBI Gene 3489, UniProtKB P24592 and related ABMIUM catalogue products.
