Anticorps primaire fourni par Boster Bio
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L'enzyme de conjugaison NEDD8 Ubc12 est une protéine qui, chez l'homme, est codée par le gène UBE2M. La modification des protéines par l'ubiquitine est un mécanisme cellulaire important pour cibler les protéines anormales ou à courte durée de vie pour la dégradation. L'ubiquitination implique au moins trois classes d'enzymes : les enzymes d'activation de l'ubiquitine, ou E1, les enzymes de conjugaison de l'ubiquitine, ou E2, et les ubiquitine-protéine ligases, ou E3. Ce gène code un membre de la famille des enzymes de conjugaison de l'ubiquitine E2. La protéine codée est liée à une protéine de type ubiquitine, NEDD8, qui peut être conjuguée à des protéines cellulaires, telles que Cdc53/culin.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Espèce | WB | IHC | IHC-P | IHC-F | IF/ICC | Cytométrie en flux | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Humain | ||||||||
| Souris | ||||||||
| Rat |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.