Anticorps primaire fourni par Boster Bio
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Le facteur de transcription SOX-9 est une protéine qui, chez l'homme, est codée par le gène SOX9. La protéine codée par ce gène reconnaît la séquence CCTTGAG avec d'autres membres des protéines de liaison à l'ADN de la classe HMG-box. Elle agit pendant la différenciation des chondrocytes et, avec le facteur stéroïdogenèse 1, régule la transcription du gène de l'hormone anti-Müllerienne (AMH). Les déficiences entraînent le syndrome de malformation squelettique, la dysplasie campomélique, fréquemment accompagnée d'un renversement sexuel.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Espèce | WB | IHC | IHC-P | IHC-F | IF/ICC | Cytométrie en flux | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Souris | ||||||||
| Rat |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
PDCD1 identifies programmed cell death 1 in Homo sapiens (Human). This target record connects NCBI Gene 5133, UniProtKB Q15116 and related ABMIUM catalogue products.
Biological function: PDCD1 encodes programmed cell death protein 1 (PD-1/CD279), an inhibitory immune receptor expressed on antigen-activated lymphocytes. Engagement by PD-L1/CD274 or PD-L2/PDCD1LG2 attenuates activation signalling and contributes to peripheral immune tolerance, making the pathway a major regulator of T-cell responses.
