Anticorps primaire fourni par Boster Bio
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Ce gène code le facteur cytosolique des neutrophiles 2, la sous-unité cytosolique de 67 kilodaltons du complexe multi-protéique NADPH oxydase trouvé dans les neutrophiles. Cette oxydase produit un éclatement de superoxyde qui est délivré à la lumière du phagosome des neutrophiles. Des mutations dans ce gène, ainsi que dans d'autres sous-unités de la NADPH oxydase, peuvent entraîner une granulomatose chronique, une maladie qui provoque des infections récurrentes par des organismes catalases-positifs. L'épissage alternatif aboutit à de multiples variants de transcription codant différentes isoformes.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Espèce | WB | IHC | IHC-P | IHC-F | IF/ICC | Cytométrie en flux | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Humain | ||||||||
| Souris | ||||||||
| Rat |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.