Anticorps primaire fourni par Boster Bio
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La neurofibromine 1 (NF1) est un gène humain situé sur le chromosome 17. Ce produit génique semble fonctionner comme un régulateur négatif de la voie de transduction du signal ras. Des mutations de ce gène ont été associées à la neurofibromatose de type 1, à la leucémie myélomonocytaire juvénile et au syndrome de Watson. L'ARNm de ce gène est soumis à un ARN-édition (CGA>UGA->Arg1306Term) entraînant une terminaison prématurée de la traduction. Des variantes de transcrits épissés alternativement encodant différentes isoformes ont également été décrites pour ce gène.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Espèce | WB | IHC | IHC-P | IHC-F | IF/ICC | Cytométrie en flux | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Humain | ||||||||
| Souris | ||||||||
| Rat |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.