Anticorps primaire fourni par Boster Bio
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La chimiokine (motif C-X-C) ligand 7 (CXCL7), également connue sous le nom de NAP2 ou protéine basique pro-plaquettaire (PPBP), est un gène humain. La protéine codée par ce gène est un facteur de croissance dérivé des plaquettes qui appartient à la famille des chimiokines CXC. Ce facteur de croissance est un puissant chimioattractant et activateur des neutrophiles. Il a été démontré qu'il stimule divers processus cellulaires, notamment la synthèse d'ADN, la mitose, la glycolyse, l'accumulation intracellulaire d'AMPc, la sécrétion de prostaglandine E2 et la synthèse d'acide hyaluronique et de glycosaminoglycane sulfaté. Il stimule également la formation et la sécrétion de l'activateur du plasminogène par les cellules synoviales. De plus, la protéine est une protéine antimicrobienne ayant une activité bactéricide et antifongique.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Espèce | WB | IHC | IHC-P | IHC-F | IF/ICC | Cytométrie en flux | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Mouse |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
PPBP identifies pro-platelet basic protein in Homo sapiens (Human). This target record connects NCBI Gene 5473, UniProtKB P02775 and related ABMIUM catalogue products.
Biological function: Pro-platelet basic protein (PPBP; platelet basic protein/CXCL7) is a platelet-derived CXC chemokine precursor that is processed into bioactive products including connective tissue-activating peptide III and neutrophil-activating peptide 2. Its products support chemokine signalling and leukocyte responses.
