Anticorps primaire fourni par Boster Bio
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La GTPase mitochondriale Rho 1 (MIRO1) est une enzyme qui, chez l'homme, est codée par le gène RHOT1 sur le chromosome 17. Le membre de la famille T1 de l'homologue Ras (RHOT) est une GTPase atypique de Rho se liant au Ca2+ qui se localise dans les mitochondries. RHOT1, la protéine apparentée RHOT2, la protéine adaptatrice Milton et la kinase putative 1 induite par PTEN (PINK1), forment un complexe impliqué dans le transport axonal des mitochondries. PINK1 et Parkin ciblent tous deux RHOT1 pour la phosphorylation et la dégradation, provoquant l'arrêt de la motilité mitochondriale.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Espèce | WB | IHC | IHC-P | IHC-F | IF/ICC | Cytométrie en flux | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Humain | ||||||||
| Souris | ||||||||
| Rat |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
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