Anticorps primaire fourni par Boster Bio
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MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1), également connu sous le nom de MACAM1, est une protéine qui, chez l'homme, est codée par le gène MADCAM1. Par analyse basée sur la PCR d'hybrides de cellules somatiques, ce gène est cartographié sur le chromosome 19. La protéine codée par ce gène est une molécule d'adhésion cellulaire endothéliale qui interagit préférentiellement avec l'intégrine bêta7 leucocytaire LPAM-1 (alpha4 / bêta7), la L-sélectine et le VLA-4 (alpha4 / bêta1) sur les cellules myéloïdes pour diriger les leucocytes vers les tissus muqueux et inflammés. C'est un membre de la superfamille des immunoglobulines et est similaire à ICAM-1 et VCAM-1.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Espèce | WB | IHC | IHC-P | IHC-F | IF/ICC | Cytométrie en flux | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Humain | ||||||||
| Rat |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
MADCAM1 identifies mucosal vascular addressin cell adhesion molecule 1 in Homo sapiens (Human). This target record connects NCBI Gene 8174, UniProtKB Q13477 and related ABMIUM catalogue products.
