Anticorps primaire fourni par Boster Bio
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La tyrosine-protéine kinase JAK3 est une enzyme qui, chez l'homme, est codée par le gène JAK3. Elle est cartographiée sur 19p13.11. La protéine codée par ce gène est un membre de la famille des Janus kinases (JAK), des tyrosine kinases impliquées dans la transduction du signal intracellulaire médiée par les récepteurs de cytokines. Elle est majoritairement exprimée dans les cellules immunitaires et transduit un signal en réponse à son activation via la phosphorylation de la tyrosine par les récepteurs d'interleukines. Les mutations de ce gène sont associées au DICS autosomique (déficit immunitaire combiné sévère).
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Espèce | WB | IHC | IHC-P | IHC-F | IF/ICC | Cytométrie en flux | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
JAK3 identifies Janus kinase 3 in Homo sapiens (Human). This target record connects NCBI Gene 3718, UniProtKB P52333 and related ABMIUM catalogue products.
