Anticorps primaire fourni par Boster Bio
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L'interleukine-1 récepteur kinase 1, également appelée IRAK1, est une enzyme qui, chez l'homme, est codée par le gène IRAK1. Par analyse de radiation hybride, ce gène est cartographié sur le chromosome Xq28. La sérine/thréonine-protéine kinase joue un rôle essentiel dans l'initiation de la réponse immunitaire innée contre les agents pathogènes étrangers. Ce gène est impliqué dans les voies de signalisation du récepteur Toll-like (TLR) et de l'IL-1R. Ce gène code pour l'interleukine-1 récepteur kinase 1, l'une des deux kinases sérine/thréonine putatives qui s'associent au récepteur de l'interleukine-1 (IL1R) lors de la stimulation. Ce gène est partiellement responsable de la régulation positive, induite par l'IL1, du facteur de transcription NF-kappa B.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Espèce | WB | IHC | IHC-P | IHC-F | IF/ICC | Cytométrie en flux | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Humain | ||||||||
| Souris | ||||||||
| Rat |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
IRAK1 identifies interleukin 1 receptor associated kinase 1 in Homo sapiens (Human). This target record connects NCBI Gene 3654, UniProtKB P51617 and related ABMIUM catalogue products.
