Anticorps primaire fourni par Boster Bio
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L'interleukine 33 (IL-33) est une protéine qui chez l'homme est codée par le gène IL33. La protéine codée par ce gène est une cytokine qui se lie au récepteur IL1RL1/ST2. La protéine codée est impliquée dans la maturation des cellules Th2 et l'activation des mastocytes, des basophiles, des éosinophiles et des cellules tueuses naturelles. Plusieurs variants de transcription codant différentes isoformes ont été trouvés pour ce gène.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Espèce | WB | IHC | IHC-P | IHC-F | IF/ICC | Cytométrie en flux | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Souris | ||||||||
| Rat |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
IL33 identifies interleukin 33 in Homo sapiens (Human). This target record connects NCBI Gene 90865, UniProtKB O95760 and related ABMIUM catalogue products.
Biological function: IL33 is an IL-1 family cytokine that signals through IL1RL1/ST2, activating NF-kappa-B and MAPK pathways. It promotes type 2 immune responses and can activate mast cells, basophils, eosinophils and natural killer cells.
