Anticorps primaire fourni par Boster Bio
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L'hyaluronidase-1, également connue sous le nom de HYAL1 ou LUCA1, est une enzyme qui, chez l'homme, est codée par le gène HYAL1. Ce gène fait partie de plusieurs gènes apparentés dans une région du chromosome 3p21.3 associée à la suppression tumorale. Ce gène code une hyaluronidase lysosomale. Les hyaluronidases dégradent intracellulairement l'hyaluronane, l'un des principaux glycosaminoglycanes de la matrice extracellulaire. L'hyaluronane est considéré comme impliqué dans la prolifération, la migration et la différenciation cellulaires. Cette enzyme est active à un pH acide et est la principale hyaluronidase du plasma. Les mutations de ce gène sont associées à la mucopolysaccharidose de type IX, ou déficit en hyaluronidase.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Espèce | WB | IHC | IHC-P | IHC-F | IF/ICC | Cytométrie en flux | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Souris | ||||||||
| Rat |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
HYAL1 identifies hyaluronidase 1 in Homo sapiens (Human). This target record connects NCBI Gene 3373, UniProtKB Q12794 and related ABMIUM catalogue products.
