Anticorps primaire fourni par Boster Bio
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La sérine protéase HTRA1 est une enzyme qui, chez l'homme, est codée par le gène HTRA1. Ce gène code un membre de la famille des sérine protéases de type trypsine. Cette protéine est une enzyme sécrétée dont on pense qu'elle régule la disponibilité des facteurs de croissance analogues à l'insuline (IGF) en clivant les protéines de liaison aux IGF. Il a également été suggéré qu'il s'agissait d'un régulateur de la croissance cellulaire. Les variations dans la région promotrice de ce gène sont la cause de la susceptibilité à la dégénérescence maculaire liée à l'âge de type 7.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Espèce | WB | IHC | IHC-P | IHC-F | IF/ICC | Cytométrie en flux | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Humain | ||||||||
| Souris | ||||||||
| Rat |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
HTRA1 identifies HtrA serine peptidase 1 in Homo sapiens (Human). This target record connects NCBI Gene 5654, UniProtKB Q92743 and related ABMIUM catalogue products.
