Primary Antibodie supplied by Boster Bio.
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The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17.
Product profile: Reactivity: Human, Mouse; Host: Rabbit; Clonality: Polyclonal; Isotype: Rabbit IgG.
Applications: WB,IHC,ELISA.
Recommended conditions: Western blot, 0.25-0.5 μg/ml, Human, Mouse<br> Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human<br> ELISA, 0.1-0.5 μg/ml<br>
Technical details: Immunogen: E.coli-derived human Gp130/IL6ST recombinant protein (Position: H71-Q918).; Purification: Immunogen affinity purified.; Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.; Observed MW: 140 kDa; Calculated MW: 104 kDa.
Storage: At -20˚C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freezing and thawing.
Research Use Only.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Species | WB | IHC | IHC-P | IHC-F | IF/ICC | Flow Cytometry | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human | ||||||||
| Mouse |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
IL6ST identifies interleukin 6 cytokine family signal transducer in Homo sapiens (Human). This target record connects NCBI Gene 3572, UniProtKB P40189 and related ABMIUM catalogue products.
