Anticorps primaire fourni par Boster Bio
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Le récepteur 1 du facteur de croissance endothélial vasculaire (FLT1) est une protéine qui, chez l'homme, est codée par le gène FLT1. L'oncogène FLT appartient à la famille des gènes src. Il est cartographié sur 13q12. La protéine déduite de 1 338 acides aminés a une masse moléculaire calculée de 150,6 kD. Elle possède un domaine extracellulaire de 758 acides aminés, suivi d'une région transmembranaire de 22 acides aminés et d'une région cytoplasmique de 558 acides aminés contenant un groupe d'acides aminés basiques et un domaine tyrosine kinase. La sFLT-1 a été identifiée dans le placenta, le poumon adulte, le rein, le foie et l'utérus. Comme les autres membres de cette famille, elle présente une activité tyrosine protéine kinase importante pour le contrôle de la prolifération et de la différenciation cellulaires.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Espèce | WB | IHC | IHC-P | IHC-F | IF/ICC | Cytométrie en flux | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
Fms related receptor tyrosine kinase 1 (FLT1), also known as vascular endothelial growth factor receptor 1 (VEGFR1), is a VEGF-family receptor. This ABMIUM record links human FLT1 (NCBI Gene 2321; UniProt P17948) to catalogue-backed products.
Biological function: FLT1/VEGFR1 is a receptor tyrosine kinase that binds vascular endothelial growth factor ligands and placental growth factor. It contributes to angiogenesis and vasculogenesis, with membrane-bound and soluble receptor isoforms.
