Anticorps primaire fourni par Boster Bio
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Le FGF2 a été impliqué dans une multitude de processus physiologiques et pathologiques, notamment le développement des membres, l'angiogenèse, la cicatrisation des plaies et la croissance tumorale. Le FGF2 humain partage 96 % et 97 % d'homologie de séquence d'acides aminés avec la souris et le rat respectivement. Le FGF2 appartient à la famille des facteurs de croissance des fibroblastes (FGF). Les facteurs de croissance des fibroblastes (FGF) présentent des activités mitogènes et neurotrophiques étendues. Neuf membres de la famille sont actuellement connus, et le FGF-1 et le FGF-2 sont présents à des niveaux relativement élevés dans le SNC. Le FGF-2 est exprimé à de faibles niveaux dans de nombreux tissus et types de cellules et atteint des concentrations élevées dans le cerveau et l'hypophyse.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Espèce | WB | IHC | IHC-P | IHC-F | IF/ICC | Cytométrie en flux | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Humain | ||||||||
| Souris | ||||||||
| Rat |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
FGF2 identifies fibroblast growth factor 2 in Homo sapiens (Human). This target record connects NCBI Gene 2247, UniProtKB P09038 and related ABMIUM catalogue products.
Biological function: FGF2 is a fibroblast growth factor that signals through FGFR1-4 and regulates cell survival, division, differentiation and migration. It is a potent mitogen and can promote angiogenesis.
