Anticorps primaire fourni par Boster Bio
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La molécule CD3e, epsilon, également connue sous le nom de CD3E, est un polypeptide qui, chez l'homme, est codé par le gène CD3E qui réside sur le chromosome 11. Il est cartographié en 11q23.3. La protéine codée par ce gène est le polypeptide CD3-epsilon, qui, avec les CD3-gamma, -delta et -zeta, et les hétérodimères alpha/bêta et gamma/delta du récepteur des lymphocytes T, forme le complexe CD3-récepteur des lymphocytes T. Ce complexe joue un rôle important dans le couplage de la reconnaissance des antigènes à plusieurs voies de transduction du signal intracellulaire. Les gènes codant les polypeptides epsilon, gamma et delta sont situés dans le même cluster sur le chromosome 11. Le polypeptide epsilon joue un rôle essentiel dans le développement des lymphocytes T.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Espèce | WB | IHC | IHC-P | IHC-F | IF/ICC | Cytométrie en flux | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Poulet | ||||||||
| Humain | ||||||||
| Souris | ||||||||
| Rat |
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CD3E identifies CD3 epsilon subunit of T-cell receptor complex in Homo sapiens (Human). This target record connects NCBI Gene 916, UniProtKB P07766 and related ABMIUM catalogue products.
