Anticorps primaire fourni par Boster Bio
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L'antigène lymphocytaire B CD19, également connu sous le nom de CD19 (Cluster de Différenciation 19), est une protéine qui, chez l'homme, est codée par le gène CD19. On le trouve à la surface des cellules B, un type de globules blancs. Les lymphocytes prolifèrent et se différencient en réponse à diverses concentrations de différents antigènes. La capacité de la cellule B à répondre de manière spécifique, mais sensible, aux divers antigènes est obtenue grâce à l'utilisation de récepteurs d'antigènes à faible affinité. Le gène CD19 code une molécule de surface cellulaire qui s'assemble avec le récepteur d'antigène des lymphocytes B afin de diminuer le seuil de stimulation dépendante du récepteur d'antigène.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Espèce | WB | IHC | IHC-P | IHC-F | IF/ICC | Cytométrie en flux | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Rat |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
CD19 molecule (CD19), also known as B-lymphocyte antigen CD19, is a B-cell surface glycoprotein and signalling coreceptor. This guide connects human NCBI Gene 930, UniProtKB P15391 and ABMIUM catalogue products associated with CD19.
Biological function: CD19 functions as a coreceptor for the B-cell antigen receptor complex, lowering the threshold for antigen-triggered B-cell activation. CD19 signalling can activate phosphatidylinositol 3-kinase pathways and mobilise intracellular calcium, supporting normal B-cell differentiation, proliferation and antibody responses.
