Anticorps primaire fourni par Boster Bio
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La protéine 9A liée à l'autophagie est une protéine qui, chez l'homme, est codée par le gène ATG9A. ATG9A est la seule protéine ATG transmembranaire essentielle à l'autophagie. Elle joue un rôle clé dans l'organisation de la structure pré-autophagosome/site d'assemblage du phagophore (PAS). Il a été rapporté que l'expression d'ATG9A est augmentée dans le carcinome épidermoïde oral et les cancers du sein. L'inhibition d'ATG9A peut entraîner une inhibition de la prolifération et de l'invasion des cellules cancéreuses.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Espèce | WB | IHC | IHC-P | IHC-F | IF/ICC | Cytométrie en flux | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Humain | ||||||||
| Souris |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
ATG9A encodes a membrane phospholipid scramblase required for expansion of the forming autophagosome. This target record connects reviewed human ATG9A identifiers with ABMIUM catalogue products targeting ATG9A.
Biological function: ATG9A is a phospholipid scramblase central to autophagosome membrane expansion. It cycles between the phagophore assembly site and cytoplasmic vesicles, redistributing phospholipids across the bilayer so that membrane supplied during autophagosome growth can expand both leaflets. ATG9A also contributes to membrane trafficking events that support autophagosome initiation.
