Rabbit Angiotensin Converting Enzyme, ACE ELISA Kit
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Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety (By similarity).
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Evidence | Serum | Plasma | Cell culture supernatants | Ascites | Tissue homogenates |
|---|---|---|---|---|---|
| Compatibility |
This product is manufactured by BT LAB and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
Angiotensin I converting enzyme (ACE), also known as angiotensin-converting enzyme, ACE1 or CD143, is a peptidase in the renin-angiotensin system. It converts angiotensin I to angiotensin II and inactivates bradykinin, making ACE a central target in blood-pressure, cardiovascular and renal physiology research.
Biological function: Angiotensin I converting enzyme (ACE; ACE1/CD143) is a peptidase in the renin-angiotensin system that converts angiotensin I to angiotensin II and also inactivates bradykinin, linking it to blood-pressure and fluid-electrolyte regulation.
