Manufactured by:BT LAB
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PRKAA1 Monoclonal Antibody

PRKAA1 Monoclonal Antibody

SKU:
ABM201847
Manufacturer SKU
BT-MCA2498
Product type
Primary Antibodies
TargetPRKAA1
ApplicationsWB, IHC-P, IF/ICC, Flow Cytometry, ELISA, IHC
Species / reactivityHuman, Monkey, Mouse, Rat

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

The protein belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Key facts & specifications
Research areas
Neuroscience
Also known as
AMPK;AMPKa1;MGC33776;MGC57364;PRKAA1
Host species
Mouse
Clonality
Monoclonal
Isotype
Mouse IgG1
Dilution range
WB: 1:500 - 1:2000; IHC-p: 1:200 - 1:1000; ICC: 1:200 - 1:1000; FCM: 1:200 - 1:400; ELISA: 1:10000
Immunogen
Purified recombinant fragment of human PRKAA1 expressed in E. Coli.
Molecular weight
64kDa
Quantity per pack
100μL, 50μL
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceWBIHC-pICCFCMELISAIHC
Applications
Identifiers & database references
Manufacturer SKU
BT-MCA2498
Gene ID
5562
UniProt accession
Q13131
Storage, stability & shipping
Storage conditions
Store at 4°C short term. Aliquot and store at -20°C long term.
Short-term storage
Store at 4°C short term.
Long-term storage
Aliquot and store at -20°C long term.
Storage buffer
Ascitic fluid containing 0.03% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

PRKAA1protein kinase AMP-activated catalytic subunit alpha 1

View target guide

PRKAA1 identifies protein kinase AMP-activated catalytic subunit alpha 1 in Homo sapiens (Human). This target record connects NCBI Gene 5562, UniProtKB Q13131 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
5562
UniProtKB
Q13131
BT LAB
£240.93£205.00