Manufactured by:BT LAB
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Smad3 Monoclonal Antibody

Smad3 Monoclonal Antibody

SKU:
ABM200489
Manufacturer SKU
BT-MCA1131
Product type
Primary Antibodies
TargetSMAD3
ApplicationsELISA, IF/ICC, WB
Species / reactivityHuman, Mouse

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.

Key facts & specifications
Research areas
Signal Transduction, Epigenetics and Nuclear Signaling, Cancer, Stem Cells, Metabolism
Also known as
SMAD3; MADH3; Mothers against decapentaplegic homolog 3; MAD homolog 3; Mad3; Mothers against DPP homolog 3; hMAD-3; JV15-2; SMAD family member 3; SMAD 3; Smad3; hSMAD3
Host species
Mouse
Clonality
Monoclonal
Isotype
IgG
Dilution range
ELISA: 1:10000; IF: 1:200 - 1:1000; WB: 1:500 - 1:2000
Immunogen
Purified recombinant fragment of human Smad3 expressed in E. Coli.
Concentration
1 mg/ml
Purification
Affinity purification
Quantity per pack
50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceELISAIFWBICC
Applications
Identifiers & database references
Manufacturer SKU
BT-MCA1131
Gene ID
4088
UniProt accession
P84022
Storage, stability & shipping
Shelf life
-20°C for one year
Storage conditions
-20°C for one year
Storage buffer
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

SMAD3SMAD family member 3

View target guide

SMAD3 identifies SMAD family member 3 in Homo sapiens (Human). This target record connects NCBI Gene 4088, UniProtKB P84022 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
4088
UniProtKB
P84022
BT LAB
£135.52£115.00