Manufactured by:BT LAB
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FAS-L Polyclonal Antibody

FAS-L Polyclonal Antibody

SKU:
ABM197663
Manufacturer SKU
BT-AP15532
Product type
Primary Antibodies
TargetFASLG
ApplicationsWB, IHC-P, IF/ICC, ELISA
Species / reactivityHuman, Mouse

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

Background

This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described.

Key facts & specifications
Research areas
Cancer, Cell Biology, Immunology, Stem Cells
Also known as
Tumor necrosis factor ligand superfamily member 6; FASLG; APT1LG1; CD95L; FASL; TNFSF6; Tumor necrosis factor ligand superfamily member 6; Apoptosis antigen ligand; APTL; CD95 ligand; CD95-L; Fas antigen ligand; Fas ligand; FasL; CD antigen CD178
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
WB: 1: 500 - 1: 2000; IHC-p: 1: 100 - 1: 300; IF: 1: 200 - 1: 1000; ICC: 1: 200 - 1: 1000; ELISA: 1: 40000
Immunogen
The antiserum was produced against synthesized peptide derived from human FAS ligand. AA range:101-150
Molecular weight
31485
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Quantity per pack
20ul, 50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceWBIHC-pIFICCELISA
Applications
Identifiers & database references
Manufacturer SKU
BT-AP15532
Gene ID
356
UniProt accession
P48023
Storage, stability & shipping
Shelf life
-20°C for 1 year
Storage conditions
-20°C for 1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

FASLGFas ligand

View target guide

FASLG identifies Fas ligand in Homo sapiens (Human). This target record connects NCBI Gene 356, UniProtKB P48023 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
356
UniProtKB
P48023
BT LAB
£81.31£69.00