Manufactured by:BT LAB
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DAPK1(Phospho Ser308) Polyclonal Antibody

DAPK1(Phospho Ser308) Polyclonal Antibody

SKU:
ABM196598
Manufacturer SKU
BT-AP15175
Product type
Primary Antibodies
TargetDAPK1
ApplicationsIHC-P, IF/ICC, ELISA
Species / reactivityHuman, Mouse

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate. Alternative splicing results in multiple transcript variants.

Key facts & specifications
Research areas
Cancer, Cell Biology, Signal Transduction
Also known as
Death-associated protein kinase 1; DAPK1; DAPK; Death-associated protein kinase 1; DAP kinase 1
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
IHC-p: 1: 100 - 1: 300; IF: 1: 200 - 1: 1000; ICC: 1: 200 - 1: 1000; ELISA: 1: 10000
Immunogen
The antiserum was produced against synthesized peptide derived from human DAPK1 around the phosphorylation site of Ser308. AA range:274-323
Molecular weight
160286
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Quantity per pack
20ul, 50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceIHC-pIFICCELISA
Applications
Identifiers & database references
Manufacturer SKU
BT-AP15175
Gene ID
1612
UniProt accession
P53355
Storage, stability & shipping
Shelf life
-20°C for 1 year
Storage conditions
-20°C for 1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

KRT18keratin 18

View target guide

Keratin 18 (KRT18), also known as cytokeratin 18, CK-18 and K18, is a type I cytoskeletal intermediate-filament protein. This ABMIUM target record connects NCBI Gene 3875 and UniProtKB P05783 to catalogue-backed research products.

Biological function: Keratin 18 (KRT18/CK-18) is a type I intermediate-filament protein expressed prominently in simple epithelial cells. It forms heteropolymeric filaments, notably with keratin 8, that contribute to cytoskeletal organisation, mechanical stability and epithelial-cell resilience.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
3875
UniProtKB
P05783
BT LAB
£81.31£69.00