Manufactured by:BT LAB
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TPH1(Phospho Ser58) Polyclonal Antibody

TPH1(Phospho Ser58) Polyclonal Antibody

SKU:
ABM196346
Manufacturer SKU
BT-AP15091
Product type
Primary Antibodies
TargetTPH1
ApplicationsWB, IHC-P, ELISA, IF/ICC
Species / reactivityHuman, Mouse, Rat

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.

Key facts & specifications
Research areas
Signal Transduction, Metabolism, Cancer, Neuroscience
Also known as
Tryptophan 5-hydroxylase 1; TPH1; TPH; TPRH; TRPH; Tryptophan 5-hydroxylase 1; Tryptophan 5-monooxygenase 1
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
WB: 1: 500 - 1: 2000; IHC-p: 1: 100 - 1: 300; ELISA: 1: 10000
Immunogen
The antiserum was produced against synthesized peptide derived from human Tryptophan Hydroxylase around the phosphorylation site of Ser58. AA range:26-75
Molecular weight
50985
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Quantity per pack
20ul, 50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceWBIHC-pELISAIF
Applications
Identifiers & database references
Manufacturer SKU
BT-AP15091
Gene ID
7166
UniProt accession
P17752
Storage, stability & shipping
Shelf life
-20°C for 1 year
Storage conditions
-20°C for 1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

TPH1tryptophan hydroxylase 1

View target guide

TPH1 identifies tryptophan hydroxylase 1 in Homo sapiens (Human). This target record connects NCBI Gene 7166, UniProtKB P17752 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
7166
UniProtKB
P17752
BT LAB
£81.31£69.00